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662098 UbcH5c Conjugating Enzyme E2, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: UBD2D3, Ubiquitin-conjugating enzyme E2 D3

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      Overview

      Description
      OverviewFull-length, recombinant, human UbcH5c expressed in E. coli. UbcH5c, an E2 ubiquitin ligase, is highly homologous to the yeast UbC4/5 family of E2 enzymes. UbcH5c, together with UbcH5a and UbcH5b, are the most active class of E2 enzymes in cell extracts and are associated with regulation of transcription factors such as p53, NF-κB3, and c-Fos. The active enzyme is useful in the study of ubiquitin regulation and inhibitor screening.
      Catalogue Number662098
      Brand Family Calbiochem®
      SynonymsUBD2D3, Ubiquitin-conjugating enzyme E2 D3
      References
      ReferencesBrzovic, P.S., et al. 2006. Cell Cycle 5, 2867.
      Gehrke, S.G., et al. 2003 Blood. 101, 3288.
      Nuber, U., And Scheffner, M., 1999. J. Biol. Chem. 274, 7576.
      Schwarz, S.E., et al. 1998. J. Biol. Chem. 273, 12148.
      Jensen, J., et al. 1995. J. Biol. Chem. 270, 30408.
      Scheffner, M., et al. 1994. Proc. Natl. Acad. Sci. 91, 8797.
      Product Information
      FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.0.
      Quality LevelMQ100
      Biological Information
      Purity≥95% by SDS-PAGE
      Concentration Label Please refer to vial label for lot-specific concentration
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      662098 0