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565950 Sialyl Lewis x, Sodium Salt - CAS 98603-84-0 - Calbiochem

Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: SLex, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc

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565950
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
98603-84-0C₃₁H₅₁NaN₂O₂₃

Pricing & Availability

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565950-1MG
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      565950-5MG
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          Description
          OverviewEnzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. SLex reduces injury following ischemia and reperfusion and immune complex-induced acute lung injury in animal models. In both of these models, SLex is presumed to act by blocking E-selectin-mediated neutrophil recruitment to sites of inflammation.
          Catalogue Number565950
          Brand Family Calbiochem®
          SynonymsSLex, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc
          References
          ReferencesSeekamp, A., et al. 1994. Am. J. Pathol. 144, 592.
          Mulligan, M.S., et al. 1993. J. Exp. Med. 178, 623.
          Ichikawa, Y., et al. 1992. J. Am. Chem. Soc. 114, 9283.
          Lasky, L.A. 1992. Science 258, 964.
          Product Information
          CAS number98603-84-0
          FormWhite solid
          Hill FormulaC₃₁H₅₁NaN₂O₂₃
          Chemical formulaC₃₁H₅₁NaN₂O₂₃
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥95% by TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Blue Ice Only
          Toxicity Standard Handling
          Storage -20°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          565950-1MG 04055977191301
          565950-5MG 04055977191318

          Documentation

          Sialyl Lewis x, Sodium Salt - CAS 98603-84-0 - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Sialyl Lewis x, Sodium Salt - CAS 98603-84-0 - Calbiochem Certificates of Analysis

          TitleLot Number
          565950

          References

          Reference overview
          Seekamp, A., et al. 1994. Am. J. Pathol. 144, 592.
          Mulligan, M.S., et al. 1993. J. Exp. Med. 178, 623.
          Ichikawa, Y., et al. 1992. J. Am. Chem. Soc. 114, 9283.
          Lasky, L.A. 1992. Science 258, 964.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision10-September-2008 RFH
          SynonymsSLex, Neu5Acα2,3Galβ1,4(Fucα1,3)GlcNAc
          DescriptionEnzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. SLex reduces injury following ischemia, reperfusion and immune complex-induced acute lung injury in animal models. In both of these models, SLex is presumed to act by blocking E-selectin-mediated neutrophil recruitment to sites of inflammation.
          FormWhite solid
          CAS number98603-84-0
          Chemical formulaC₃₁H₅₁NaN₂O₂₃
          Structure formulaStructure formula
          Purity≥95% by TLC
          SolubilityH₂O (2 mg/ml)
          Storage -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesSeekamp, A., et al. 1994. Am. J. Pathol. 144, 592.
          Mulligan, M.S., et al. 1993. J. Exp. Med. 178, 623.
          Ichikawa, Y., et al. 1992. J. Am. Chem. Soc. 114, 9283.
          Lasky, L.A. 1992. Science 258, 964.

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          Categories

          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Carbohydrates > Lewis Series