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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

444270 Sigma-AldrichMMP-7, Active, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA
References
Data Sheet
Citations

Synonyms: Matrilysin, rhMMP-7, PUMP-1

Recommended Products

Overview

Replacement Information

Pricing & Availability

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Description
Overview	Recombinant, human MMP-7 expressed in E. coli. MMP-7, the smallest member of the matrix metalloproteinase family that can degrade a wide range of gelatins, proteoglycans, and glycoproteins of the matrix and can activate several other MMPs.
Catalogue Number	444270
Brand Family	Calbiochem®
Synonyms	Matrilysin, rhMMP-7, PUMP-1

References
References	Kivelä-Rajamäki, M., et al. 2003. J. Periodont. Res. 38, 583. Woessner, J.F. 1995. Methods Enzymol. 248, 485. Crabbe, T., et al. 1992. Biochemistry 31, 8500.

Product Information
Unit of Definition	One unit is defined as the amount of enzyme that will digest 1.0 µg AZOCOLL™ Substrate (Cat. No. 194933) per min at 37°C, pH 7.5.
EC number	3.4.24.23
Form	Liquid
Formulation	In 150 mM NaCl, 10 mM HEPES, 5 mM CaCl₂, pH 7.4.
Quality Level	MQ100

Applications

Biological Information
Specific Activity	≥3000 units/mg protein

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
Catalogue Number	GTIN
444270-100UG	04055977186574

Documentation

MMP-7, Active, Human, Recombinant, E. coli SDS

Title
Safety Data Sheet (SDS)

MMP-7, Active, Human, Recombinant, E. coli Certificates of Analysis

Title	Lot Number
444270	Enter Lot Number

References

Reference overview
Kivelä-Rajamäki, M., et al. 2003. J. Periodont. Res. 38, 583. Woessner, J.F. 1995. Methods Enzymol. 248, 485. Crabbe, T., et al. 1992. Biochemistry 31, 8500.

Citations

Title

Douglas Ethell, Ross Kinloch and Douglas Green. (2002) Metalloproteinase Shedding of Fas Ligand Regulates β-Amyloid Neurotoxicity. Current Biology 12, 1595-1600.

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	07-August-2008 RFH
Synonyms	Matrilysin, rhMMP-7, PUMP-1
Description	Recombinant, human MMP-7 expressed in E. coli. MMP-7 is the smallest member of the matrix metalloproteinase family that can degrade a wide range of gelatins, proteoglycans, and glycoproteins of the matrix and activate several other MMPs.
Form	Liquid
Formulation	In 150 mM NaCl, 10 mM HEPES, 5 mM CaCl₂, pH 7.4.
EC number	3.4.24.23
Specific activity	≥3000 units/mg protein
Unit definition	One unit is defined as the amount of enzyme that will digest 1.0 µg AZOCOLL™ Substrate (Cat. No. 194933) per min at 37°C, pH 7.5.
Storage	Avoid freeze/thaw ≤ -70°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).
Toxicity	Standard Handling
References	Kivelä-Rajamäki, M., et al. 2003. J. Periodont. Res. 38, 583. Woessner, J.F. 1995. Methods Enzymol. 248, 485. Crabbe, T., et al. 1992. Biochemistry 31, 8500.
Citation	Douglas Ethell, Ross Kinloch and Douglas Green. (2002) Metalloproteinase Shedding of Fas Ligand Regulates β-Amyloid Neurotoxicity. Current Biology 12, 1595-1600.

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