Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
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-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
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506072
Sigma-AldrichInSolution™ Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem
A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2) in DMSO.
More>>A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2) in DMSO. Less<<
MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: N-(6-Methylbenzo[d]thiazol-2-yl)-2-(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-ylthio)acetamide, Wnt Pathway Inhibitor II InSolution, Inhibitor of Wnt Production-2, Porcn Inhibitor I InSolution, InSolution Wnt Antagonist II, IWP-2, Wnt Antagonist II, IWP-2 InSolution
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Description
Catalogue Number
506072
Brand Family
Calbiochem®
Synonyms
N-(6-Methylbenzo[d]thiazol-2-yl)-2-(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-ylthio)acetamide, Wnt Pathway Inhibitor II InSolution, Inhibitor of Wnt Production-2, Porcn Inhibitor I InSolution, InSolution Wnt Antagonist II, IWP-2, Wnt Antagonist II, IWP-2 InSolution
References
References
Chen, B., et al. 2009. Nature Chem. Biol.5, 100.
Product Information
CAS number
686770-61-6
Form
Liquid
Formulation
A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2 (Cat. No. 681671) in DMSO.
Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. Slight warming to 60°C may be required upon initial thaw.
Packaging Information
Packaged under inert gas
Packaged under inert gas
Global Trade Item Number
Catalogue Number
GTIN
5.06072.0001
04055977243055
Documentation
InSolution™ Wnt Antagonist II, IWP-2 - CAS 686770-61-6 - Calbiochem SDS
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
26-August-2024
Synonyms
N-(6-Methylbenzo[d]thiazol-2-yl)-2-(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-ylthio)acetamide, Wnt Pathway Inhibitor II InSolution, Inhibitor of Wnt Production-2, Porcn Inhibitor I InSolution, InSolution Wnt Antagonist II, IWP-2, Wnt Antagonist II, IWP-2 InSolution
Description
A cell-permeable benzothiazolyl-acetamide compound that inhibits the cellular Wnt processing and secretion via selective blockage of MBOAT (membrane-bound O-acyltranferase) family member Porcn- (Porcupine) mediated Wnt palmitoylation. IWP-2 does not affect Wnt/β-catenin signaling pathway in general and, unlike IWR-1-endo (Cat. No. 681669), displays no effect against Wnt-stimulated cellular responses.
Form
Liquid
Formulation
A 10 mM (5 mg/1.07 ml) sterile-filtered solution of Wnt Antagonist II, IWP-2 (Cat. No. 681671) in DMSO.
Intert gas (Yes/No)
Packaged under inert gas
CAS number
686770-61-6
Chemical formula
C₂₂H₁₈N₄O₂S₃
Structure formula
Purity
≥99% by HPLC
Storage
Protect from light Avoid freeze/thaw ≤ -70°C Hygroscopic
Do Not Freeze
Ok to freeze
Special Instructions
Following initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C. Slight warming to 60°C may be required upon initial thaw.
