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324744 Elastase Inhibitor II - Calbiochem

The Elastase Inhibitor II controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Elastase Inhibitor II - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: HNE Inhibitor, MeOSuc-AAPA-CMK, MSACK

Primary Target: Human neutrophil elastase (HNE)
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324744
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₀H₃₁ClN₄O₇

Pricing & Availability

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324744-5MG
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      Description
      OverviewA potent irreversible inhibitor of human neutrophil elastase (HNE). Inhibition results from cross-linking of the catalytic residues His57 and Ser195.
      Catalogue Number324744
      Brand Family Calbiochem®
      SynonymsHNE Inhibitor, MeOSuc-AAPA-CMK, MSACK
      References
      ReferencesNavia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
      Williams, H.R., et al. 1987. J. Biol. Chem. 262, 17178.
      Product Information
      ATP CompetitiveN
      FormWhite lyophilized solid
      Hill FormulaC₂₀H₃₁ClN₄O₇
      Chemical formulaC₂₀H₃₁ClN₄O₇
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetHuman neutrophil elastase (HNE)
      Purity≥99% by TLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceMeOSuc-Ala-Ala-Pro-Ala-CMK
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      324744-5MG 04055977216059

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Elastase Inhibitor II - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Elastase Inhibitor II - Calbiochem Certificates of Analysis

      TitleLot Number
      324744

      References

      Reference overview
      Navia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
      Williams, H.R., et al. 1987. J. Biol. Chem. 262, 17178.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-October-2009 JSW
      SynonymsHNE Inhibitor, MeOSuc-AAPA-CMK, MSACK
      DescriptionA potent inhibitor of human neutrophil elastase (HNE).The inhibition results from cross-linking of catalytic residues His57 and Ser195 in the HNE in the presence of this inhibitor.
      FormWhite lyophilized solid
      Chemical formulaC₂₀H₃₁ClN₄O₇
      Peptide SequenceMeOSuc-Ala-Ala-Pro-Ala-CMK
      Structure formulaStructure formula
      Purity≥99% by TLC
      SolubilityDMSO (10 mg/ml) or Methanol
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesNavia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
      Williams, H.R., et al. 1987. J. Biol. Chem. 262, 17178.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Elastase Inhibitors
      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors