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ABS564 Anti-Serpinf2 Antibody

This Anti-Serpinf2 antibody is validated for use in WB, IH for the detection of Serpinf2.

Anti-Serpinf2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: SERPINF2, AAP, PLI UniProt Number: P08697
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ABS564
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABS564
      DescriptionAnti-Serpinf2 Antibody
      Alternate Names
      • Alpha-2-antiplasmin
      • Alpha-2-AP
      • Alpha-2-plasmin inhibitor
      • Alpha-2-PI
      • Serpin F2
      Background InformationSerpin F2, also known as Alpha-2-antiplasmin Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, and encoded by the gene name SERPINF2, AAP, or PLI, is a member of the Serpin family. Serpin F2 is a serine protease inhibitor. As an inhibitor, the major targets of Serpin F2 are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. Serpin F2 forms protease inhibiting heterodimer with TMPRSS7. Serpin F2 is expressed by the liver and secreted in plasma. Mutations in Serpin F2 have been associated with Alpha-2-plasmin inhibitor deficiency (APLID), an autosomal recessive disorder resulting in severe hemorrhagic diathesis.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Serpinf2 antibody is validated for use in WB, IH for the detection of Serpinf2.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Serpinf2 in human liver and human liver cancer tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the Alpha-2-antiplasmin mature chain of human Serpinf2.
      EpitopeAlpha-2-antiplasmin mature chain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Species Reactivity NoteHuman. Predicted to react with Primate based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SERPINF2
      • AAP
      • PLI
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~73 kDa observed. Predicated to work with both glycos and non-glycos isoforms.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human liver tissue lysate.

      Western Blotting Analysis: 2.0 µg/mL of this antibody detected Serpinf2 in 10 µg of human liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS564 04055977117059