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ABE999 Anti-RPB3

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ABE999
100 µL  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, R, MWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE999
      DescriptionAnti-RPB3
      Alternate Names
      • RPB3
      • DNA-directed RNA polymerase II subunit RPB3
      • RNA polymerase II subunit 3
      • RNA polymerase II subunit B3
      • DNA-directed RNA polymerase II 33 kDa polypeptide
      • DNA-directed RNA polymerase II subunit C
      • RPB31
      Background InformationRPB3 is one of 12 subunits that make up the complete RNA polymerase, Pol II, the primary RNA polymerase in cellular metabolism. RPB3 is part of the core element of Pol II complex. RPB3 has a central large cleft and the clamp element that moves to open and close the cleft during RNA synthesis. RPB3 naturally localizes to the nucleus and expressed in all cell types and tissues. RPB3 also plays critical roles in RNA splicing and capping, key items of RNA function.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-RPB3 Antibody is an antibody against RPB3 for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human RPB3 near the Near C-terminus.
      EpitopeNear C-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      • Rat
      • Mouse
      Species Reactivity NoteHuman, Rat, Mouse. Predicted to react with Bovine based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • POLR2C
      • A-152E5.7
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~35 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HUVEC cell lysate.

      Western Blotting Analysis: A 1:500 dilution of this antibody detected RPB3 in 10 µg of HUVEC cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABE999 04055977135350

      Documentation

      Anti-RPB3 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-RPB3 Certificates of Analysis

      TitleLot Number
      Anti-RPB3 - 3173786 3173786
      Anti-RPB3 - 3735352 3735352
      Anti-RPB3 - 3764357 3764357
      Anti-RPB3 - 3982598 3982598
      Anti-RPB3 - 4062249 4062249
      Anti-RPB3 - 4198987 4198987
      Anti-RPB3 -Q2550840 Q2550840
      Anti-RPB3 Polyclonal Antibody - 3932875 3932875

      Brochure

      Title
      NPI Flyer- Epigenetics and Nuclear Function Feature
      New Products - Antibodies, Small Molecule, Inhibitors

      Technical Info

      Title
      White Paper: Further considerations of antibody validation and usage.