Anti-Mechano Growth Factor (MGF) Antibody

Mechano growth factor (MGF) is initially produced as a precursor (pro-MGF) from an mRNA species containing exons 5 and 6 of the IGF-I gene as a result of alternate splicing of the pro-IGF-1 mRNA in response to mechanical stimuli, such as tenectomy or eletrical stimulation. Exon 5 sequence-containing IGF-1 mRNA or the protein product is referred to as MGF, or Eb in rodents and Ec in human (PMID 20130113). Cat. no. 07-2108, Anti-Mechano Growth Factor (MGF), recognizes both pro- and mature MGF, but not IGF-I.

~15/8 kDa observed.

Epitope: E peptide domain

KLH-conjugated linear peptide corresponding to the E peptide domain of mouse Mechano Growth Factor (MGF).

Anti-Mechano Growth Factor (MGF) Antibody is an antibody against Mechano Growth Factor (MGF) for use in Immunohistochemistry (Paraffin), Western Blotting, Immunofluorescence.

Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Mechano Growth Factor (MGF) in human prostate cancer and human cerebellum tissue.
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Mechano Growth Factor (MGF) in MGF recombinant protein (Heidi Scrable, University of Virginia).
Immunofluorescence Analysis: A 1:5,000 dilution from a representative lot detected Mechano Growth Factor (MGF) in mouse hypothalamus cells (Heidi Scrable, University of Virginia).

Research Category
Signaling

Research Sub Category
Signaling Neuroscience

This antibody does not cross-react with IGF1.

Affinity

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Immunohistochemistry in human cerebral cortex tissue.

Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Mechano Growth Factor (MGF) in human cerebral cortex tissue.

Concentration: Please refer to lot specific datasheet.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.