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ABN1023 Anti-LILRB2 Antibody

Anti-LILRB2 Antibody is an antibody against LILRB2 for use in Western Blotting, Immunohistochemistry .

Anti-LILRB2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: LILRB2, ILT4, LIR2, MIR10 UniProt Number: Q8N423
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ABN1023
100 μg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABN1023
      DescriptionAnti-LILRB2 Antibody
      Alternate Names
      • Leukocyte immunoglobulin-like receptor subfamily B member 2
      • LIR-2
      • Leukocyte immunoglobulin-like receptor 2
      • CD85 antigen-like family member D
      • Immunoglobulin-like transcript 4
      • ILT-4
      • Monocyte/macrophage immunoglobulin-like receptor 10
      • MIR-10
      • CD85d
      • LILRB2
      Background InformationLeukocyte immunoglobulin-like receptor subfamily B member 2 (UniProt Q8N423; also known as CD85 antigen-like family member D, CD85d, Ig-like transcript 4, ILT-4, Leukocyte immunoglobulin-like receptor 2, LIR-2, MIR-10, Monocyte/macrophage immunoglobulin-like receptor 10) is encoded by the LILRB2 (also known as CD85D, ILT4, LIR2, MIR10) gene (Entrez Gene ID 10288) in human. CD85d belongs to the B class of leukocyte immunoglobulin-like (LIR) receptors family, members of which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Cd85d is expressed on immune cells and negatively regulates immune response by engaging class I MHC molecules (HLA-A, HLA-B, HLA-C) on antigen-presenting cells.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-LILRB2 Antibody is an antibody against LILRB2 for use in Western Blotting, Immunohistochemistry .
      Key Applications
      • Western Blotting
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected LILRB2 in human ovarian cancer tumor cells, mouse cerebral cortex, human brain cancer tumor cells, mouse hippocampus, and Non-Hodgkin lymphoma cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the extracellular domain of human LILRB2.
      EpitopeExtracellular domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityReacts with all 4 known human CD85d isoforms.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • LILRB2
      • ILT4
      • LIR2
      • MIR10
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~64/120 kDa observed. The calculated molecular weight of the four isoforms range from ~52 to ~65 kDa, a band with apparent molecular weight above ~110 kDa is often seen on blots as a result of glycosylation.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Jurkat cell lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected LILRB2 in 10 µg of Jurkat cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABN1023 04055977169188