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MABN317 Anti-BM88/Cend1 Antibody, clone 4A3.1

Anti-BM88/Cend1 Antibody, clone 4A3.1 is an antibody against BM88/Cend1 for use in western blotting & IHC.

Anti-BM88/Cend1 Antibody, clone 4A3.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: CEND1, BM88 UniProt Number: Q8N111
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MABN317
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN317
      DescriptionAnti-BM88/Cend1 Antibody, clone 4A3.1
      Alternate Names
      • Cell cycle exit and neuronal differentiation protein 1
      • BM88 antigen
      Background InformationBM88/Cend1, also known as Cell cycle exit and neuronal differentiation protein 1, or BM88 antigen, and encoded by the gene Cend1/BM88, is a neuronal specific membrane protein that is involved in neuronal development. BM88/Cend1 is particularly important in cerebellar development including Purkinje cell differentiation as well as radial glia guided migration of cerebellar granule cell development. Overexpression of BM88/CEND1 in transplanted neural stem cells also appears to enhance the regeneration of neuronal cells in injured rodent brains. BM88/Cend1 function is at least partially mediated through interacting with the important developmental protein Ahi1, and research indicates that BM88/Cend1 is also involved in Ahi1-associated hypothalamic neuronal differentiation in early development.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-BM88/Cend1 Antibody, clone 4A3.1 is an antibody against BM88/Cend1 for use in western blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50-2,000 dilution from a representative lot detected BM88/Cend1 in human cerebellum, human thalamus sections, and rat cerebral cortex tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the cytoplasmic domain of human BM88/Cend1.
      EpitopeCytoplasmic domain
      Clone4A3.1
      Concentration1 mg/mL
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • CEND1
      • BM88
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~19 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human cortex tissue lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected BM88/Cend1 in 10 µg of human cortex tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN317 04053252973932