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ABS184 Anti-AMPylated Tyrosine Antibody

Anti-AMPylated Tyrosine Antibody detects level of AMPylated Tyrosine & has been published & validated for use in Western Blotting.

Anti-AMPylated Tyrosine Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: General Post-translation Modification
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ABS184
100 µL  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbSerumPolyclonal Antibody
      Description
      Catalogue NumberABS184
      DescriptionAnti-AMPylated Tyrosine Antibody
      Alternate Names
      • AMPylated Tyrosine
      Background InformationAMPylation is a reversible post-translational modification in which adenosine monophosphate (AMP) derived from ATP is added to threonine and tyrosine (and possibly serine) residues on target proteins. This modification is created by proteins containing Fic (filamentation induced by cyclic adenosine monophosphate) domains, which are present in both prokaryotic and eukaryotic cells. In mammals, the HYPE protein is the most widely known Fic-containing protein and the precise function of its AMPylated targets is not yet clear. However, bacterial cells possess numerous Fic-domain proteins that modify and disable protein targets in host cells, thereby suppressing signaling pathways and increasing the robustness of pathogenic infections. The Vibrio parahaemolyticus VopS protein, for instance, disrupts the function of Rho guanine triphosphatases, and eventually disrupts the actin cytoskeleton.
      References
      Product Information
      FormatSerum
      Control
      • Rac1, AMPylated in vitro
      PresentationRabbit polyclonal serum containing 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-AMPylated Tyrosine Antibody detects level of AMPylated Tyrosine & has been published & validated for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      HostRabbit
      SpecificityThis antibody recognizes AMPylated Tyrosines.
      IsotypeIgG
      Species Reactivity
      • Human
      Species Reactivity NoteDemonstrated to react with Human. Broad species reactivity expected, as AMPylation is evolutionarily conserved.
      Antibody TypePolyclonal Antibody
      Purification MethodUnpurified
      Molecular Weight~21 kDa observed. Molecular weights will vary based on the protein being AMPylated.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in Rac1, AMPylated in vitro.

      Western Blot Analysis: A 1:1,000 dilution of this antibody detected AMPylated Tyrosine on 10 ng of Rac1, AMPylated in vitro.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABS184 04053252439247

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Anti-AMPylated Tyrosine Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-AMPylated Tyrosine Antibody Certificates of Analysis

      TitleLot Number
      Anti-AMPylated Tyrosine - 2450771 2450771
      Anti-AMPylated Tyrosine - 2341112 2341112
      Anti-AMPylated Tyrosine - 2512049 2512049
      Anti-AMPylated Tyrosine - 3216004 3216004
      Anti-AMPylated Tyrosine - 3839094 3839094
      Anti-AMPylated Tyrosine - 4299514 4299514
      Anti-AMPylated Tyrosine - Q2005661 Q2005661
      Anti-AMPylated Tyrosine -2890952 2890952
      Anti-AMPylated Tyrosine Polyclonal Antibody 2929154
      Anti-AMPylated Tyrosine Polyclonal Antibody 3091980
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      Brochure

      Title
      New Products: Volume 3, 2012

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies