567300 Sigma-AldrichSKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem
Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system.
More>> Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system. Less<<Synonyms: Proadifen
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Overview
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Key Spec Table
CAS # | Empirical Formula |
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62-68-0 | C₂₃H₃₁NO₂ . HCl |
Products
Catalogue Number | Packaging | Qty/Pack | |
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567300-1GM | Plastic ampoule | 1 gm |
Product Information | |
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CAS number | 62-68-0 |
ATP Competitive | N |
Form | White solid |
Hill Formula | C₂₃H₃₁NO₂ . HCl |
Chemical formula | C₂₃H₃₁NO₂ . HCl |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Biological Information | |
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Primary Target | nNOS |
Primary Target IC<sub>50</sub> | 90 µM against neuronal nitric oxide synthase |
Purity | ≥98% by TLC |
Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS | |
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RTECS | YV7175000 |
Safety Information | |
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R Phrase | R: 22 Harmful if swallowed. |
S Phrase | S: 36 Wear suitable protective clothing. |
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Packaging Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalogue Number | GTIN |
567300-1GM | 04055977267181 |
Documentation
SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem SDS
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SKF-525A, Hydrochloride - CAS 62-68-0 - Calbiochem Certificates of Analysis
Title | Lot Number |
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567300 |
References
Reference overview |
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Hecker, M., et al. 1994. J. Neurochem. 62, 1524. Sakuta, H. and Yoneda, I. 1994. Eur. J. Pharmacol. 252, 117. Khan, S., et al. 1993. Biochem. Pharmacol. 45, 439. Boeynaems, J.M., et al. 1986. Prostaglandins 32, 145. Lee, C.H., et al. 1976. J. Pharmacol. Exp. Ther. 198, 347. Grasdalen, J., et al. 1975. FEBS Lett. 60, 240. |
Brochure
Title |
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Pathways and Biomarkers of Oxidative Stress |