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106757 Methyl 4-hydroxybenzoate

EMPROVE® EXPERT Ph Eur,BP,ChP,JP,NF

Methyl 4-hydroxybenzoate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Methylparaben, 4-Hydroxybenzoic acid methyl ester

CAS #: 99-76-3 EC Number: 202-785-7 Molar Mass: 152.15 g/mol Chemical Formula: 4-(OH)C₆H₄(COOCH₃) Hill Formula: C₈H₈O₃ Grade: Ph Eur,BP,ChP,JP,NF
106757
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
99-76-3202-785-7C₈H₈O₃4-(OH)C₆H₄(COOCH₃)152.15 g/molPh Eur,BP,ChP,JP,NF

Products

Catalogue NumberPackaging Qty/Pack
1067575000 Fibre carton 5 kg
1067579024 Double PE Sack 20 kg
Description
Catalogue Number106757
SynonymsMethylparaben, 4-Hydroxybenzoic acid methyl ester
DescriptionMethyl 4-hydroxybenzoate
References
Product Information
CAS number99-76-3
EC number202-785-7
GradePh Eur,BP,ChP,JP,NF
Hill FormulaC₈H₈O₃
Chemical formula4-(OH)C₆H₄(COOCH₃)
Molar Mass152.15 g/mol
HS Code2918 29 22
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.38 g/cm3 (20 °C)
Flash point168 °C Not applicable
Ignition temperature>600 °C
Melting Point125 °C
pH value5.72 (1.88 g/l, H₂O, 20 °C) (saturated solution)
Vapor pressure<1 hPa (20 °C)
Bulk density300 - 400 kg/m3
Solubility1.88 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 2100 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H411: Toxic to aquatic life with long lasting effects.
Precautionary Statement(s)P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/ container to an approved waste disposal plant.
RTECSDH2450000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 3077 , 9, III
Declaration (transport by air) IATA-DGRUN 3077 , 9, III
Declaration (transport by sea) IMDG-CodeUN 3077 , 9, III, Marine Pollutant: P
Supplemental Information
Specifications
Assay (HPLC, Ph. Eur., BP, JP, NF)98.0 - 102.0 %
Assay (HPLC, calc. on dried substance) (ChP)98.0 - 102.0 %
Identity (IR-spectrum)passes test
Identity (melting range)passes test
Identity (HPLC) (ChP)passes test
Identity (UV-spectrum)passes test
Appearance of solution (100 g/l, Ethanol 96 %)clear and not more intense in color than reference solution BY₆
Appearance of solution (100 g/l, ethanol 96 %) (ChP)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₁ or YG₁
Aciditypasses test
Melting range (lower value)≥ 125 °C
Melting range (upper value)≤ 128 °C
Chloride (Cl)≤ 350 ppm
Sulfate (SO₄)≤ 240 ppm
As (Arsenic)≤ 1 ppm
Heavy metals (as Pb)≤ 10 ppm
Related substances (HPLC, Ph. Eur., BP, ChP, JP, NF)passes test
p-Hydroxy benzoic acid≤ 0.3 %
Largest unspecified impurity≤ 0.4 %
Sum of all impurities≤ 0.8 %
Methanol (HS-GC)≤ 3000 ppm
Other residual solvents (ICH Q3C)excluded by manufactoring process
Sulfated ash (600 °C)≤ 0.1 %
Residue on ignition (500 °C)≤ 0.1 %
Loss on drying (room temperature, vacuum)≤ 0.5 %
Total aerobic microbial count (TAMC)≤ 10²
Total combined yeasts/moulds count (TYMC)≤ 10²
Endotoxins≤ 200 I.U./g
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Not for food use.
Corresponds to Ph Eur, BP, ChP, JP, NF.
Global Trade Item Number
Catalogue Number GTIN
1067575000 04022536081847
1067579024 04022536938677

Documentation

Material Qualification Dossier

TitleVersion
8.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Methyl 4-hydroxybenzoate SDS

Title

Safety Data Sheet (SDS) 

Methyl 4-hydroxybenzoate Certificates of Analysis

Product Number PackagingSpecificationLot Number
1067575000 Fibre cartonPDF Specification Document
1067579024 Double PE SackPDF Specification Document

Certificates

Title