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14-615 MINK Protein, active, 10 µg

Active, N-terminal His6-tagged, recombinant, human MINK amino acids 1-310, for use in Kinase Assays.

MINK Protein, active, 10 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-615
10 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-615
Brand Family Upstate
Trade Name
  • Upstate
DescriptionMINK Protein, active, 10 µg
OverviewN-terminal His6-tagged, recombinant, human MINK amino acids 1-310
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal His6-tagged, recombinant, human MINK amino acids 1-310, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Sourceexpressed by baculovirus in Sf21 insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
Gene Symbol
  • MINK1
  • hMINK
  • ZC3
  • MINK
  • MAP4K6
  • B55
  • hMINKbeta
  • YSK2
  • MGC21111
Protein TargetMINK
Purification MethodNi2+/NTA-agarose
Target Sub-FamilySTE
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q8N4C8 # Serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in the development of the brain (By similarity).
COFACTOR: Magnesium (By similarity).
SIZE: 1332 amino acids; 149810 Da
TISSUE SPECIFICITY: Expressed in the brain, isoform 2 is more abundant than isoform 1.
SIMILARITY: SwissProt: Q8N4C8 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 CNH domain. & Contains 1 protein kinase domain.
Molecular Weight38.7kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of MBP
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
14-615 04053252731051