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12-420 Long S6 Kinase Substrate Peptide

Long S6 Kinase Substrate Peptide MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
12-420
1 mg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number12-420
Brand Family Upstate
Trade Name
  • Upstate
DescriptionLong S6 Kinase Substrate Peptide
References
Product Information
PresentationLyophilized
Quality LevelMQ100
Applications
Key Applications
  • Kinase Assay
Biological Information
Entrez Gene Number
Entrez Gene SummaryThis gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene Symbol
  • RPS6KA1
  • pp90RSK1
  • HU-1
  • RSK-1
  • MAPKAPK1A
  • p90S6K
  • RSK1
  • RSK
Protein Targetp70S6K
Target Sub-FamilyAGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q15418 # Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.
COFACTOR: Magnesium.
SIZE: 735 amino acids; 82723 Da
SUBUNIT: Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.
PTM: Autophosphorylated on Ser-380, as part of the activation process.
SIMILARITY: SwissProt: Q15418 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 2 protein kinase domains.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated as a substrate for ROK (Catalogue No. 14-338) and other kinases.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions2 years at 4°C
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
12-420 04053252372988

Documentation

Long S6 Kinase Substrate Peptide SDS

Title

Safety Data Sheet (SDS) 

Long S6 Kinase Substrate Peptide Certificates of Analysis

TitleLot Number
Long S6 Kinase Substrate Peptide 3028347
Long S6 Kinase Substrate Peptide 2959010
Long S6 Kinase Substrate Peptide 2928462
Long S6 Kinase Substrate Peptide 2970719
Long S6 Kinase Substrate Peptide 3046207
Long S6 Kinase Substrate Peptide 3089178
Long S6 Kinase Substrate Peptide - 1947714 1947714
Long S6 Kinase Substrate Peptide - 2026379 2026379
Long S6 Kinase Substrate Peptide - 20298 20298
Long S6 Kinase Substrate Peptide - 23236 23236
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Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Kinase & Phosphatase Substrates
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Kinase & Phosphatase Substrates