566321 Sigma-AldrichInSolution™ Sirtinol - Calbiochem
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Primary Target:
ySir2
InSolution™ Sirtinol - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide, Sir Two Inhibitor Naphthol, SIRT1 Inhibitor I, SIRT1/2 Inhibitor I, SIRT2 Inhibitor III
Recommended Products
Overview
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Key Spec Table
| Empirical Formula |
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| C₂₆H₂₂N₂O₂ |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 566321-1MG | Plastic ampoule | 1 mg |
| References | |
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| References | Mai, A., et al. 2005. J. Med. Chem. 48, 7789. Grozinger, C.M., et al. 2001. J. Biol. Chem. 276, 38837. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Liquid |
| Formulation | A 10 mM (1 mg/254 µl) solution of Sirtinol (Cat. No. 566320) in DMSO. |
| Hill Formula | C₂₆H₂₂N₂O₂ |
| Chemical formula | C₂₆H₂₂N₂O₂ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | ySir2 |
| Primary Target IC<sub>50</sub> | 48 µM, 131 µM and 58 µM for ySir2, hSIRT1 and hSIRT2, respectively |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 566321-1MG | 04055977191387 |
Documentation
InSolution™ Sirtinol - Calbiochem SDS
| Title |
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InSolution™ Sirtinol - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 566321 |
References
| Reference overview |
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| Mai, A., et al. 2005. J. Med. Chem. 48, 7789. Grozinger, C.M., et al. 2001. J. Biol. Chem. 276, 38837. |
Data Sheet
| Title |
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| SIRTainty™ Class III HDAC Assay |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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