573130 Sigma-AldrichInSolution™ STAT3 Inhibitor VI, S3I-201 - Calbiochem
The InSolution™ STAT3 Inhibitor VI, S3I-201, also referenced under CAS 501919-59-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation &
More>> The InSolution™ STAT3 Inhibitor VI, S3I-201, also referenced under CAS 501919-59-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Overview
Key Spec Table
| Empirical Formula |
|---|
| C₁₆H₁₅NO₇S |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 573130-5MG | Glass bottle | 5 mg |
| Description | |
|---|---|
| Overview | A cell-permeable amidosalicylic acid compound that binds Stat3-SH2 domain and prevents Stat3 phosphorylation/activation, dimerization, DNA-binding, and Stat3-dependent transcription. Shown to arrest Stat3-dependent tumor growth both in cultures in vitro (effective conc. ≤100 µM) and in a murine xenograft model in vivo (5 mg/kg, i.v.). The solid form of this compound (Cat. No. 573102) is also available. |
| Catalogue Number | 573130 |
| Brand Family | Calbiochem® |
| References | |
|---|---|
| References | Lin, L., et al. 2009. Oncogene, 28, 961. Siddiquee, K., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 7391. |
| Product Information | |
|---|---|
| Form | Liquid |
| Formulation | A 50 mM (5 mg/274 µl) solution of STAT3 Inhibitor VI, S3I-201 (Cat. No. 573102) in DMSO. |
| Hill Formula | C₁₆H₁₅NO₇S |
| Chemical formula | C₁₆H₁₅NO₇S |
| Hygroscopic | Hygroscopic |
| Structure formula Image | |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Purity | ≥95% by HPLC |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 573130-5MG | 04055977190205 |