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14-568M Fgr Protein, active, 250 µg

Active, N-terminal His6-tagged, recombinant, human Fgr, amino acids 2-end, for use in Kinase Assays.

Fgr Protein, active, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-568M
250 µg  Also available in 10 μg size (cat#14-568) and in bulk (cat# 14-568-K).
Purchase on Sigma-Aldrich

Overview

Description
Catalogue Number14-568M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionFgr Protein, active, 250 µg
OverviewN-terminal His6-tagged, recombinant, human Fgr, amino acids 2-end
Product Information
Quality LevelMQ300
Applications
ApplicationActive, N-terminal His6-tagged, recombinant, human Fgr, amino acids 2-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceExpressed by baculovirus in Sf21 insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryThis gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Gene Symbol
  • FGR
  • P55-FGR
  • p58c-fgr
  • MGC75096
  • c-src2
  • p55c-fgr
  • SRC2
  • c-fgr
  • FLJ43153
Protein TargetFgr
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyTK
UniProt Number
UniProt SummarySIZE: 529 amino acids; 59479 Da
SUBUNIT: Binds PTPNS1 (By similarity).
SIMILARITY: SwissProt: P09769 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Molecular Weight60.4kDa
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-568) and in bulk (cat# 14-568-K).
Global Trade Item Number
Catalogue Number GTIN
14-568M 04053252369582