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324740 Elastase Substrate V, Fluorogenic - CAS 72252-90-5 - Calbiochem

Elastase Substrate V, Fluorogenic, CAS 72252-90-5, is a sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 µM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: MeOSuc-AAPV-AMC

324740
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
324740-25MG Plastic ampoule 25 mg
Description
OverviewSensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 µM; kcat/Km = 120,000 M-1 s-1). Not hydrolysed by cathepsin G.
Catalogue Number324740
Brand Family Calbiochem®
SynonymsMeOSuc-AAPV-AMC
References
ReferencesBarrett, A.J. 1981. Methods Enzymol. 80, 581.
Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
Product Information
CAS number72252-90-5
ATP CompetitiveN
FormWhite to off-white lyophilized solid or powder
Hill FormulaC₃₁H₄₁N₅O₉
Chemical formulaC₃₁H₄₁N₅O₉
ReversibleN
Quality LevelMQ200
Applications
Biological Information
Primary TargetSensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase
Primary Target IC<sub>50</sub>Km = 140 µM; kcat/Km = 120,000 M⁻¹ s⁻¹as substrates for human leukocyte and porcine pancreatic elastase
Purity≥95% by HPLC or TLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-AMC
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
324740-25MG 04055977216042

Documentation

Elastase Substrate V, Fluorogenic - CAS 72252-90-5 - Calbiochem Certificates of Analysis

TitleLot Number
324740

References

Reference overview
Barrett, A.J. 1981. Methods Enzymol. 80, 581.
Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision09-April-2018 JSW
SynonymsMeOSuc-AAPV-AMC
DescriptionSensitive fluorogenic substrate for the quantitative determination of human leukocyte (Km = 140 µM; Kcat/Km = 120,000 s-1 M-1) and porcine pancreatic elastase. Not hydrolyzed by cathepsin G. Excitation max.: ~380 nm; emission max.: ~460 nm.
FormWhite to off-white lyophilized solid or powder
CAS number72252-90-5
Chemical formulaC₃₁H₄₁N₅O₉
Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-AMC
Purity≥95% by HPLC or TLC
SolubilityDMSO (5 mg/ml), DMF (5 mg/ml), or Ethanol (1 mg/ml)
Storage Protect from moisture
Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
Toxicity Standard Handling
ReferencesBarrett, A.J. 1981. Methods Enzymol. 80, 581.
Castillo, M.J., et al. 1979. Anal. Biochem. 99, 53.
Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.