288500 Sigma-AldrichDL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem
A cell-permeable, anticancer agent that acts as a specific and irreversible inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis.
More>> A cell-permeable, anticancer agent that acts as a specific and irreversible inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: DFMO, Eflornithine, RMI-71782
Recommended Products
Overview
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Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 96020-91-6 | C₆H₁₂F₂N₂O₂ · HCl · H₂O |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 288500-25MG | Glass bottle | 25 mg |
| Product Information | |
|---|---|
| CAS number | 96020-91-6 |
| ATP Competitive | N |
| Form | White powder |
| Hill Formula | C₆H₁₂F₂N₂O₂ · HCl · H₂O |
| Chemical formula | C₆H₁₂F₂N₂O₂ · HCl · H₂O |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | ODC |
| Purity | ≥99% by TLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS | |
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| RTECS | RM2981900 |
| Safety Information | |
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| R Phrase | R: 40 Limited evidence of a carcinogenic effect. |
| S Phrase | S: 22-36 Do not breathe dust. Wear suitable protective clothing. |
| Product Usage Statements |
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| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 288500-25MG | 04055977197921 |
Documentation
DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem SDS
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DL-α-Difluoromethylornithine, Hydrochloride - CAS 96020-91-6 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 288500 |
References
| Reference overview |
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| Meyskens, F.L., Jr., and Gerner, E.W. 1995. J. Cell. Biochem. (Suppl.) 22, 126. Feuerstein, B.G., et al. 1992. Cancer Res. 52, 6782. Takigawa, M., et al. 1990. Cancer Res. 50, 4131. Weeks, C.E., et al. 1982. Proc. Natl. Acad. Sci. USA 79, 6028. Danzin, C., et al. 1979. Life Sci. 24, 519. |
Brochure
| Title |
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| Pathways and Biomarkers of Oxidative Stress |