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137003 Citric acid monohydrate

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
5949-29-1201-069-1C₆H₈O₇ * H₂O210.14 g/molPh Eur,BP,ChP,JP,USP

Products

Catalogue NumberPackaging Qty/Pack
1370031000 Plastic bottle 1 kg
1370035000 Plastic bottle 5 kg
1370039012 Bucket, plastic 12 kg
Description
Catalogue Number137003
Synonyms2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
References
Product Information
CAS number5949-29-1
EC number201-069-1
GradePh Eur,BP,ChP,JP,USP
Hill FormulaC₆H₈O₇ * H₂O
Molar Mass210.14 g/mol
HS Code2918 14 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.54 g/cm3 (20 °C)
Flash point173.9 °C Not applicable
Melting Point135 - 152 °C
pH value1.8 (50 g/l, H₂O, 20 °C)
Vapor pressure<1 Pa (25 °C)
Bulk density800 - 1000 kg/m3
Solubility880 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 3000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statement(s)P261: Avoid breathing dust.
P264: Wash skin thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear eye protection/ face protection.
P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Signal WordWarning
RTECSGE7810000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Categories of dangerirritant
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (alkalimetric, calculated on anhydrous substance)99.5 - 100.5 %
Identity (IR-spectrum)passes test
Identity (wet chemistry)passes test
Appearancewhite to almost white or colorless crystals
Appearance of solution (200 g/l; water)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₇, BY₇ or GY₇
Chloride (Cl)≤ 5 ppm
Sulfate (SO₄)≤ 50 ppm
Heavy metals (as Pb)≤ 5 ppm
Al (Aluminium)≤ 0.2 ppm
As (Arsenic)≤ 1 ppm
Ca (Calcium)passes test
Fe (Iron)≤ 10 ppm
Oxalates (as C₂H₂O₄)≤ 360 ppm
Oxalate (C₂H₂O₄) (ChP)passes test
Residual solvents (ICH (Q3C))excluded by manufacturing process
Readily carbonisable substancepasses test
Sulfated ash (600 °C)≤ 0.05 %
Water (according to Karl Fischer)7.5 - 9.0 %
Total aerobic microbial count (TAMC)≤ 100 CFU/g
Total combined yeasts/moulds count (TYMC)≤ 10 CFU/g
Bile-tolerant gram-negative bacteria (absent in 1 g)passes test
Candida albicans (absent in 1 g)passes test
Escherichia coli (absent in 1 g)passes test
Pseudomonas aeruginosa (absent in 1 g)passes test
Salmonella (absent in 10 g)passes test
Staphylococcus aureus (absent in 1 g)passes test
DNases (Exo- and endonucleases)not detectable
RNasesnot detectable
Bacterial endotoxins< 10

Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, ChP, JP, USP
Global Trade Item Number
Catalogue Number GTIN
1370031000 04027269364946
1370035000 04027269061432
1370039012 04027269077426

Documentation

Material Qualification Dossier

TitleVersion
9.0

Quality Management Dossier (Open Access)

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Operational Excellence Dossier

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Citric acid monohydrate SDS

Title

Safety Data Sheet (SDS) 

Citric acid monohydrate Certificates of Analysis

Product Number PackagingSpecificationLot Number
1370031000 Plastic bottlePDF Specification Document
1370035000 Plastic bottlePDF Specification Document
1370039012 Bucket, plasticPDF Specification Document

Certificates

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