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SCT261 BioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator

SCT261
15 μg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberSCT261
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DescriptionBioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator
OverviewThis product is a cell-membrane-permeable, perylene-based probe for use in live cell cultures. The compound specifically localizes in mitochondria due to the triphenylphosphonium moiety. It is therefore optimal for monitoring lipid peroxidation in ferroptosis.


IMPORTANT APPLICATION NOTES:
Prepare 0.1 mM stock solution by dissolving the 5ug of SCT261 in 50 uL DMSO. Lyophilized probe may be difficult to see, confirm with yellow color of working solution.
Protect solution from light and use within the same day.
Dilute with Hanks' HEPES buffer to prepare 0.1 to 0.5 uM working solution.



SPECTRAL PROPERTIES
λex: 452 nm
λem: 470 nm
Suitable for use with FITC/GFP laser or filter
Alternate Names
  • mitochondria live cell probe
  • mitochondrial lipid peroxidation probe
  • mitochondrial ferroptosis live cell probe
Background InformationBioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator is a cell-membrane-permeable, perylene-based dye. It specifically localizes to mitochondria via introduction of the triphenylphosphonium moiety. SCT261 is used to monitor lipid peroxidation in ferroptosis research.
With excitation and emission wavelengths of 452 nm and 470 nm respectively, this probe can be applied for lipophilic peroxide imaging in living cells.
References
Product Information
Detection methodFluorescence Flow cytometry
FormatLyophilized solid
PresentationLyophilized. Yellow to yellow/orange crystalline solid.
Quality LevelMQ100
Applications
ApplicationThis probe is designed for the detection of lipid peroxidation in live cells by fluorescent microscopy or flow cytometry.
Key Applications
  • Fluorescence
  • Cell Based Assays
  • Flow Cytometry
  • Fluorescence Activated Cell Sorting (FACS)
Application NotesLive cell probe for fluorescent detection of lipid peroxidation in mitochondria by fluorescence microscopy or flow cytometry. SCT261 is an essential tool for ferroptosis research in live cell models.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assurance
Purity: ≥ 80% confirmed by HPLC. Authenticated by NMR.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore BioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator at 2 - 8 °C, protected from light.
Packaging Information
Material Size15 μg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
SCT261 04065269218142

Documentation

BioTracker™ Mitochondrial Lipid Peroxide Live Cell Ferroptosis Indicator SDS

Title

Safety Data Sheet (SDS) 

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