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SCT084 BioTracker™ MemBright 560 Live Cell Dye

Red/orange fluorescent probe for efficient, selective labeling of the plasma membrane in live cells. Suitable for superresolution microscopy.

SCT084
50 µL  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberSCT084
DescriptionBioTracker™ MemBright 560 Live Cell Dye
OverviewThe BioTracker™ Membright-560 live cell dye is a “turn-on” fluorescence probe emitting in the orange to red spectrum for imaging of plasma membranes of live cells.

Probes specific for the plasma membrane are essential for demarcating cell boundaries. Membright dyes use a novel fluorogenic mechanism, operating in a self-quenched nanoparticle state. On contact and propagation within the cell membrane, fluorescence is turned on, producing a bright signal with low to no background. The Membright live cell membrane probes are compatible with two-photon imaging, superresolution microscopy, and can be used in live or fixed cells. Their robust photostability and lack of cytotoxicity make Membright probes optimal for protracted live cell imaging. The superior characteristics of these plasma membrane probes permit use in a diverse spectrum of fluorescence detection applications.

Spectral Properties
Fluorescence images obtained by λex = 560 nm and emission range of 567-750 nm.

Reference

Collot M et al. MemBright: A family of fluorescent membrane probes for advanced cellular imaging and neuroscience. Cell Chem. Biol. 2019, 26:600-614
Alternate Names
  • Live cell membrane probe, orange/red
  • Live cell imaging probe
References
Product Information
Detection methodFluorescence
PresentationMagenta solution
Quality LevelMQ100
Applications
ApplicationRed/orange fluorescent probe for efficient, selective labeling of the plasma membrane in live cells. Suitable for superresolution microscopy.
Key Applications
  • Cell Based Assays
  • Neuroscience
  • Flow Cytometry
Application NotesLive cell fluorescent imaging, flow cytometry
Biological Information
Molecular Weight1370.3
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssurancePurity: ≥ 98% confirmed by HPLC, HNMR, LC-MS and elemental analysis.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore long term at -20°C, protected from light.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
SCT084 04065268041222