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PF126 Bcl-2, C-Terminal Truncated, His•Tag®, Human, Recombinant, E. coli

PF126
Purchase on Sigma-Aldrich

Overview

Products

Catalogue NumberPackaging Qty/Pack
PF126-50UG Glass bottle 50 μg
Description
OverviewRecombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His•Tag® sequence, and expressed in E. coli. The truncated protein retains the ability to neutralize pro-apoptotic Bcl-2 family members.
Catalogue NumberPF126
Brand Family Calbiochem®
Product Information
FormLiquid
FormulationIn 100 mM KCl, 10 mM HEPES, 20% glycerol, pH 8.0.
Quality LevelMQ100
Applications
Key Applications
Application NotesNeutralization (see biological activity)
Biological Information
Biological activityEC₅₀ = 100-300 nM based on its ability to inhibit 54 nM caspase-8-cleaved human Bid-mediated release of cytochrome c from isolated mouse liver mitochondria
Purity≥95% by SDS-PAGE
Species Reactivity
  • Human
Concentration Label Please refer to vial label for lot-specific concentration
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Global Trade Item Number
Catalogue Number GTIN
PF126-50UG 04055977226904