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MABC95 Anti-S1PR2/EDG5 Antibody, clone 6E8.1

Anti-S1PR2/EDG5 Antibody, clone 6E8.1 detects level of S1PR2/EDG5 & has been published & validated for use in Western Blotting, IHC(P).

Anti-S1PR2/EDG5 Antibody, clone 6E8.1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: S1PR2, EDG5 UniProt Number: O95136
MABC95
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, IH(P)MPurifiedMonoclonal Antibody
Description
Catalogue NumberMABC95
DescriptionAnti-S1PR2/EDG5 Antibody, clone 6E8.1
Alternate Names
  • Sphingosine 1-phosphate receptor 2
  • S1P receptor 2
  • S1P2
  • Endothelial differentiation G-protein coupled receptor 5
  • Sphingosine 1-phosphate receptor Edg-5
  • S1P receptor Edg-5
Background InformationSphingosine 1-phosphate receptor 2 (S1PR2), otherwise known as EDG5, is a ubiquitous G-protein coupled receptor for lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi, G12/13, and Gq pathways to regulate a number of second messengers and effector molecules, including cAMP, PLC, MAPK, RhoA, and Rac. S1PR2 mediates the effects of S1P on cell motility and embryonic development, among other cellular processes.
References
Product Information
FormatPurified
Control
  • Human liver tissue lysate
PresentationPurified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-S1PR2/EDG5 Antibody, clone 6E8.1 detects level of S1PR2/EDG5 & has been published & validated for use in Western Blotting, IHC(P).
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A representative lot detected S1PR2/EDG5 in human tonsil, liver, colorectal cancer tissues.
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to the cytoplasmic domain of human S1PR2/EDG5.
EpitopeCytoplasmic domain
Clone6E8.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody recognizes the cytoplasmic domain of S1PR2/EDG5.
IsotypeIgMκ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • S1PR2
  • EDG5
UniProt Number
Molecular Weight~35 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in human liver tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected S1PR2/EDG5 in 10 mg of human liver tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABC95 04053252697753

Documentation

Anti-S1PR2/EDG5 Antibody, clone 6E8.1 SDS

Title

Safety Data Sheet (SDS) 

Anti-S1PR2/EDG5 Antibody, clone 6E8.1 Certificates of Analysis

TitleLot Number
Anti-S1PR2/EDG5, Clone 6E8.1 - 4155348 4155348
Anti-S1PR2/EDG5, clone 6E8.1 - 2262715 2262715
Anti-S1PR2/EDG5, clone 6E8.1 - 3403488 3403488
Anti-S1PR2/EDG5, clone 6E8.1 - 3502139 3502139
Anti-S1PR2/EDG5, clone 6E8.1 - 3743896 3743896
Anti-S1PR2/EDG5, clone 6E8.1 - 4019759 4019759
Anti-S1PR2/EDG5, clone 6E8.1 - Q2029731 Q2029731
Anti-S1PR2/EDG5, clone 6E8.1 -2500706 2500706
Anti-S1PR2/EDG5, clone 6E8.1 -2610508 2610508
Anti-S1PR2/EDG5, clone 6E8.1 -2676713 2676713
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