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ABN478 Anti-LFG Antibody

ABN478
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MWB, IHCRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABN478
DescriptionAnti-LFG Antibody
Alternate Names
  • Protein lifeguard 2
  • Fas apoptotic inhibitory molecule 2
  • Neural membrane protein 35
  • Transmembrane BAX inhibitor motif-containing protein 2
  • LFG
Background InformationProtein lifeguard 2 (LFG) is an antiapoptotic protein belonging to the BI1 family. LFG inhibits the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-death signal. LFG is expressed at high levels in the brain especially in the hippocampus. It is also highly expressed in breast cancer tissues and correlates with the grade of tumor (grade II/grade III) in primary breast tumors.
References
Product Information
FormatAffinity Purified
Control
  • EL4 cell lysate
PresentationPurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect LFG using this rabbit polyclonal antibody, Anti-LFG Antibody validated for use in western blotting & IHC.
Key Applications
  • Western Blotting
  • Immunohistochemistry
Application NotesImmunohistochemistry Analysis: 5 µg/mL from a representative lot detected LFG in mouse brain tissue.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human LFG.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Mouse
Species Reactivity NoteDemonstrated to react with Mouse. Predicted to react with Human based on immunogen design.
Antibody TypePolyclonal Antibody
Gene Symbol
  • FAIM2
  • LFG
  • LFG2
  • NMP35
  • TMBIM2
Purification MethodAntigen Affinity Purified
UniProt Number
Molecular Weight~35 kDa observed.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in EL4 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected LFG in 15 µg of EL4 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABN478 04053252870453