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MABN683 Anti-ETV5 Antibody, clone 3H3

Anti-ETV5 Antibody, clone 3H3 is a highly specific mouse monoclonal antibody & that targets Ets & has been tested in western blotting.

Anti-ETV5 Antibody, clone 3H3 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: ERM, ETV5 UniProt Number: P41161
MABN683
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMAscitesMonoclonal Antibody
Description
Catalogue NumberMABN683
DescriptionAnti-ETV5 Antibody, clone 3H3
Alternate Names
  • ETS translocation variant 5
  • Ets-related protein ERM
  • ETV5
Background InformationETS family members play an important role in mammalian development and have been implicated in the regulation of gene expression during a variety of biologic processes including cell growth and differentiation. Defects or deficiencies, as well as overexpression of ETS family members can have major developmental effects as well as aid in tumor development. ETS translocation variant 5 protein (ETV5) also known as ETS-related protein ERM is a nuclear localized protein that binds to DNA sequences containing the consensus nucleotide core sequence of GGAA and is a member of the very large ETS transcription factor family. Early experiments in worms suggested that ETV5 might play a role in the development of the dopaminergic nervous system; however that has not proved to be the case in mammals. However, more recent research has indicated ETV5 playing an important role in the development of reproduction and in the development of ovarian cancer. ETV5 controls the expression of critical prostaglandins needed for ovarian development and ETV5 deficient mice show complex infertility phenotypes both in males and females. In males, the infertility phenotype exhibited by ETV5 deficiency is sexually dimorphic, and it involves both somatic cells and germ cells. In Etv5-/- female mice, the problem is more complicated by hormonal involvement and results in more a complex phenotype. EMD-Millipore’s Anti-ETV5 mouse monoclonal antibody has been tested in western blot against Jurkat, NIH3T3 and MCF-7 cell lysates.
References
Product Information
FormatAscites
Control
  • Jurkat, NIH/3T3 and MCF-7 cell lysates
PresentationMouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-ETV5 Antibody, clone 3H3 is a highly specific mouse monoclonal antibody & that targets Ets & has been tested in western blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenPurified recombinant fragment of human ETV5 expressed in E. Coli.
Clone3H3
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • ERM
  • ETV5
Purification MethodUnpurified
UniProt Number
Molecular Weight~58 kDa observed. Uncharacterized bands may appear in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Jurkat, NIH/3T3 and MCF-7 cell lysates.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected ETV5 in Jurkat, NIH/3T3 and MCF-7 cell lysates.

Optimal working dilutions must be determined by end user.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN683 04053252917493

Documentation

Anti-ETV5 Antibody, clone 3H3 SDS

Title

Safety Data Sheet (SDS) 

Anti-ETV5 Antibody, clone 3H3 Certificates of Analysis

TitleLot Number
Anti-ETV5, clone 3H3 - VP1401286 VP1401286
Anti-ETV5, clone 3H3 - QVP1305163 QVP1305163
Anti-ETV5, clone 3H3 -VP1502260 VP1502260
Anti-ETV5, clone 3H3 -VP1602242 VP1602242
Anti-ETV5, clone 3H3 -VP1607212 VP1607212
Anti-ETV5, clone 3H3 Monoclonal Antibody VP1810191
Anti-ETV5, clone 3H3 Monoclonal Antibody VP1804272
Anti-ETV5, clone 3H3 Monoclonal Antibody VP1707284