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176002 Anti-Angiopoietin-2 Rabbit pAb

Anti-Angiopoietin-2, rabbit polyclonal, recognizes the ~55 kDa non-glycosylated and the ~70 kDa glycosylated, secreted Ang-2 protein. It is validated for ELISA, WB, IF, and IHC.

Anti-Angiopoietin-2 Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Ang-2

176002
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
MRbPolyclonal Antibody

Products

Catalogue NumberPackaging Qty/Pack
176002-50UG Plastic ampoule 50 μg
Description
OverviewRecognizes both the ~55 kDa non-glycosylated and the ~70 kDa glycosylated, secreted Ang-2 protein in cell culture medium. Does not cross-react with Ang-1.
  • Antibody Target Gene Symbol: ANGPT2
  • Target Synonym: AGPT2, ANG II, ANG-2, ANGIOPOIETIN, ANGIOPOIETIN 2, Angiotensin 2, Angrp
  • Entrez Gene Name: angiopoietin 2
  • Hu Entrez ID: 285
  • Mu Entrez ID: 11601
  • Rat Entrez ID: 89805
    		•
    Catalogue Number176002
    Brand Family Calbiochem®
    SynonymsAnti-Ang-2
    References
    ReferencesMaisonpierre, P.C., et al. 1997. Science 277, 55.
    Davis, S., et al. 1996. Cell 87, 1161.
    Suri, S. et al. 1996. Cell 87, 1171.
    Product Information
    FormLiquid
    FormulationIn PBS, 0.1% BSA, pH 7.5.
    PreservativeNone
    Quality LevelMQ100
    Applications
    Key Applications Enzyme-Linked Immunosorbent Assay
    Immunoblotting (Western Blotting)
    Immunofluorescence
    Immunohistochemistry
    Application NotesELISA (0.1-1 µg/ml)
    Immunoblotting (1-10 µg/ml)
    Immunofluorescence (2-20 µg/ml)
    Immunohistochemistry (2-20 µg/ml)
    Application CommentsThe immunogenic peptide sequence is 71% (15/21 amino acids) conserved in the human angiopoietin-2 protein. Does not cross-react with angiopoietin-1. Variables associated with assay conditions will dictate the optimal working dilution.
    Biological Information
    Immunogena synthetic peptide corresponding to a 21 amino acid cytoplasmic sequence at the N-terminus of mouse angiopoietin-2
    ImmunogenMouse
    HostRabbit
    IsotypeIgG
    Species Reactivity
    • Mouse
    Antibody TypePolyclonal Antibody
    Concentration Label Please refer to vial label for lot-specific concentration
    Physicochemical Information
    Dimensions
    Materials Information
    Toxicological Information
    Safety Information according to GHS
    Safety Information
    Product Usage Statements
    Storage and Shipping Information
    Ship Code Dry Ice Only
    Toxicity Standard Handling
    Storage -20°C
    Avoid freeze/thaw Avoid freeze/thaw
    Do not freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Packaging Information
    Transport Information
    Supplemental Information
    Specifications
    Global Trade Item Number
    Catalogue Number GTIN
    176002-50UG 04055977222944

    Documentation

    Anti-Angiopoietin-2 Rabbit pAb SDS

    Title

    Safety Data Sheet (SDS) 

    Anti-Angiopoietin-2 Rabbit pAb Certificates of Analysis

    TitleLot Number
    176002

    References

    Reference overview
    Maisonpierre, P.C., et al. 1997. Science 277, 55.
    Davis, S., et al. 1996. Cell 87, 1161.
    Suri, S. et al. 1996. Cell 87, 1171.
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision06-May-2008 JSW
    SynonymsAnti-Ang-2
    ApplicationELISA (0.1-1 µg/ml)
    Immunoblotting (1-10 µg/ml)
    Immunofluorescence (2-20 µg/ml)
    Immunohistochemistry (2-20 µg/ml)
    DescriptionImmunoaffinity purified rabbit polyclonal antibody. Recognizes both the ~55 kDa nonglycosylated and the ~70 kDa glycosylated forms of angiopoietin-2.
    BackgroundAngiopoietin (Ang-2) is a recently identified secreted protein that may act as an antagonist for Ang-1 and Tie-2. Ang-1 and Ang-2 have ~60% sequence homology. Ang-2 expression is abundant in the dorsal aorta and major aortic branches. Ang-2 transcripts in fetal liver are restricted to cells at the lumen of hepatic vessels. In adults, Ang-2 is prominently expressed in tissues that may undergo vascular remodeling (ovary, placenta, and uterus).
    HostRabbit
    Immunogen speciesMouse
    Immunogena synthetic peptide corresponding to a 21 amino acid cytoplasmic sequence at the N-terminus of mouse angiopoietin-2
    IsotypeIgG
    Speciesmouse
    FormLiquid
    FormulationIn PBS, 0.1% BSA, pH 7.5.
    Concentration Label Please refer to vial label for lot-specific concentration
    PreservativeNone
    CommentsThe immunogenic peptide sequence is 71% (15/21 amino acids) conserved in the human angiopoietin-2 protein. Does not cross-react with angiopoietin-1. Variables associated with assay conditions will dictate the optimal working dilution.
    Storage Avoid freeze/thaw
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Toxicity Standard Handling
    ReferencesMaisonpierre, P.C., et al. 1997. Science 277, 55.
    Davis, S., et al. 1996. Cell 87, 1161.
    Suri, S. et al. 1996. Cell 87, 1171.