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116802 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt, CAS 30275-80-0, is a cell-permeable, potent activator of PKA type 1 & 2. Binds to the cAMP binding site 2 on the regulatory unit of PKA.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 6-Bnz-cAMP, Na

Primary Target: PKA
116802
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
30275-80-0C₁₇H₁₅N₅O₇P · Na

Products

Catalogue NumberPackaging Qty/Pack
116802-10UMOL Glass bottle 10 umol
Description
OverviewA potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Activates both type 1 and type 2 PKA and binds to the cAMP binding site 2 on the regulatory subunit of PKA. It is only slowly metabolized by cyclic nucleotide-dependent phosphodiesterases. Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems.
Note: 10 µmol = 4.55 mg.
Catalogue Number116802
Brand Family Calbiochem®
Synonyms6-Bnz-cAMP, Na
References
ReferencesDøskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.
Product Information
CAS number30275-80-0
ATP CompetitiveN
FormLyophilized
Hill FormulaC₁₇H₁₅N₅O₇P · Na
Chemical formulaC₁₇H₁₅N₅O₇P · Na
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationAdenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt, CAS 30275-80-0, is a cell-permeable, potent activator of PKA type 1 & 2. Binds to the cAMP binding site 2 on the regulatory unit of PKA.
Biological Information
Primary TargetPKA
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
116802-10UMOL 04055977208207

Documentation

Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem Certificates of Analysis

TitleLot Number
116802

References

Reference overview
Døskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-September-2007 RFH
Synonyms6-Bnz-cAMP, Na
DescriptionA potent, non-degradable, cell-permeable analog of cAMP that binds to the cAMP binding site 2 on the protein kinase A (PKA) regulatory subunit and activates both type I and II PKA. λmax = 279 nm (H2O, pH 7.0); εmax = 17,000 M-1cm-1.
FormLyophilized
CAS number30275-80-0
Chemical formulaC₁₇H₁₅N₅O₇P · Na
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O (10 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesDøskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.