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100030 Acetonitrile

Acetonitrile gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur. Acetonitrile CAS 75-05-08, molar mass 41.05 g/mol, and chemical formula CH₃CN.

Acetonitrile MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: ACN, Methyl cyanide, Ethyl nitrile, Cyanomethane

CAS #: 75-05-8 EC Number: 200-835-2 Molar Mass: 41.05 g/mol Chemical Formula: CH₃CN Hill Formula: C₂H₃N Grade: Reag. Ph Eur
100030
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
75-05-8200-835-2C₂H₃NCH₃CN41.05 g/molReag. Ph Eur

Products

Catalogue NumberPackaging Qty/Pack
1000302500 Glass bottle 2.5 l
1000309010 Barrel stainl. st. 10 l
1000309030 Barrel stainl. st. 30 l
1000309185 Barrel stainl. st. 185 l
Description
Catalogue Number100030
SynonymsACN, Methyl cyanide, Ethyl nitrile, Cyanomethane
OverviewWith their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in "gradient grade" as well as "isocratic grade". This enables to minimize the gradient effect of the solvent involved.
References
Product Information
CAS number75-05-8
EC index number608-001-00-3
EC number200-835-2
GradeReag. Ph Eur
Hill FormulaC₂H₃N
Chemical formulaCH₃CN
Molar Mass41.05 g/mol
HS Code2926 90 99
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationAcetonitrile gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur. Acetonitrile CAS 75-05-08, molar mass 41.05 g/mol, and chemical formula CH₃CN.
Biological Information
Physicochemical Information
Boiling point81.6 °C (1013 hPa)
Density0.78 g/cm3 (20 °C)
Explosion limit3.0 - 17 %(V)
Flash point2 °C
Ignition temperature524 °C
Melting Point-45.7 °C
Vapor pressure98.64 hPa (20 °C)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H225: Highly flammable liquid and vapour.
H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
H319: Causes serious eye irritation.
Precautionary Statement(s)P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal WordDanger
RTECSAL7700000
Storage class3 Flammable liquids
WGKWGK 2 obviously hazardous to water
Disposal1
Strongly contaminated halogen-free organic solvents: container A.
Safety Information
Categories of dangerhighly flammable, harmful, irritant
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 1648 , 3, II
Declaration (transport by air) IATA-DGRUN 1648 , 3, II
Declaration (transport by sea) IMDG-CodeUN 1648 , 3, II
Supplemental Information
Specifications
Purity (GC)≥ 99.9 %
Identity (IR)conforms
Evaporation residue≤ 2.0 mg/l
Water≤ 0.02 %
Color≤ 10 Hazen
Density (d 20 °C/20 °C)0.78
Refractive index (n 20/D)1.344
Boiling range (80-82°C)≥ 95 % (v/v)
Acidity≤ 0.0002 meq/g
Alkalinity≤ 0.0002 meq/g
Gradient grade (at 210 nm)≤ 1.0 mAU
Gradient grade (at 254 nm)≤ 0.5 mAU
Fluorescence (as quinine at 254 nm)≤ 1.0 ppb
Fluorescence (as quinine at 365 nm)≤ 0.5 ppb
Transmission (at 193 nm)≥ 60 %
Transmission (at 195 nm)≥ 80 %
Transmission (from 230 nm)≥ 98 %
Filtered by 0.2 µm filter.
Suitable for UPLC / UHPLC /Ultra HPLC - instruments.
Conforms to Acetonitrile for chromatography and Acetonitrile R1 according to Reag.Ph Eur;
conforms to the requirements of ACS for liquid chromatography suitability.
Global Trade Item Number
Catalogue Number GTIN
1000302500 04022536000893
1000309010 04022536000916
1000309030 04022536000923
1000309185 04022536000930

Documentation

Acetonitrile SDS

Title

Safety Data Sheet (SDS) 

Acetonitrile Certificates of Analysis

Product Number PackagingSpecificationLot Number
1000302500 Glass bottlePDF Specification Document
1000309010 Barrel stainl. st.PDF Specification Document
1000309030 Barrel stainl. st.PDF Specification Document
1000309185 Barrel stainl. st.PDF Specification Document

Brochure

Title
UHPLC 2 - Guidelines for high throughput separations

Technical Info

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Application Notes

Title
Antifungal medication (Standards) - separation of Itraconazole & impurities - using a Chromolith® HighResolution RP-18e column
Eye medication (Standards) - separation of Bimatoprost & free acid - using a Chromolith® HighResolution RP-18e column
Eye medication (Standards) - separation of Travoprost & free acid - using a Chromolith® HighResolution RP-18e column
Fungicides (E232 Standards) - separation of Phenylphenols - using a Chromolith® HighResolution RP-18e column
Nootropic drug (Standards) - separation of Levetiracetam and Caffeine - using a Chromolith® HighResolution RP-18e column
Organic acids (Standards) - separation of 9 Carboxylic and Aromatic acids - using a Chromolith® HighResolution RP-18e column
Peptides & Proteins (Standards) - separation of Lysozyme - using a Chromolith® HighResolution RP-18e column
Steroids (Standards) - separation of Prednisolone, Estradiol, Ethinyl-Estradiol, Estrone and Progesterone - using a Chromolith® HighResolution RP-18e column

Related Products & Applications

Accessories (Primary)

Catalogue Number Description
101123 Withdrawal system for solvents
106710 Withdrawal system for stainless steel barrels and drums
108803 Drum key
109996 Adapter S 40
901748 Dip tube
902592 Dip tube
902698 Pressure safety device 0.5 bar
963533 Safety carrier
964205 Reducing valve, 0.2 bar with 2 tube connections 6 x 8 mm and integrated excess pressure safety device 0.5 bar

Accessories (Secondary)

Catalogue Number Description
100801 Label set acc. GHS
103830 HPLC-bottle adapter with 3 tube connections ID 3.2 mm, solvents supply
103831 HPLC bottle adapter S40 with 3 tube connections and 1 connection for exhaust air filter, solvents disposal
103833 Exhaust air filter for HPLC bottle adapter S40, disposal
107070 Antistatic device
108801 Bottle key

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Categories

Reagents, Chemicals and Labware > Solvents > Solvents for Instrumental Organic Analysis > Solvents for Liquid Chromatography, LiChrosolv®
Analytics and Sample Preparation > Analytical Chromatography > Mobile Phases for Chromatography > Solvents for Liquid Chromatography, LiChrosolv®