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344039 cFMS Receptor Inhibitor IV - CAS 959626-45-0 - Calbiochem

The cFMS Receptor Inhibitor IV, also referenced under CAS 959626-45-0, controls the biological activity of cFMS. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

cFMS Receptor Inhibitor IV - CAS 959626-45-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide, CSF-1 Receptor Inhibitor IV

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344039
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
959626-45-0C₂₂H₂₆N₄O₂

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      Description
      OverviewA cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM).
      Catalogue Number344039
      Brand Family Calbiochem®
      Synonyms5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide, CSF-1 Receptor Inhibitor IV
      References
      ReferencesPatch, R.J., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6070.
      Product Information
      CAS number959626-45-0
      FormYellow solid
      Hill FormulaC₂₂H₂₆N₄O₂
      Chemical formulaC₂₂H₂₆N₄O₂
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      344039-5MG 04055977194517

      Documentation

      cFMS Receptor Inhibitor IV - CAS 959626-45-0 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      cFMS Receptor Inhibitor IV - CAS 959626-45-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      344039

      References

      Reference overview
      Patch, R.J., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6070.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-April-2011 RFH
      Synonyms5-Cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide, CSF-1 Receptor Inhibitor IV
      DescriptionA cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM).
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number959626-45-0
      Chemical formulaC₂₂H₂₆N₄O₂
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesPatch, R.J., et al. 2007. Bioorg. Med. Chem. Lett. 17, 6070.