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14-478M Yes Protein, active, 250 µg

Active, recombinant full-length human Yes, containing additional N-terminal His6 tag, for use in Kinase Assays.

Yes Protein, active, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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14-478M
250 µg  Also available in 10 μg size (cat#14-478) and in bulk (cat# 14-478-K).
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      Overview

      Replacement Information
      Description
      Catalogue Number14-478M
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionYes Protein, active, 250 µg
      OverviewRecombinant full-length human Yes, containing additional N-terminal His6 tag
      References
      Product Information
      Quality LevelMQ100
      Applications
      ApplicationActive, recombinant full-length human Yes, containing additional N-terminal His6 tag, for use in Kinase Assays.
      Key Applications
      • Kinase Assay
      Biological Information
      SourceExpressed by baculovirus in Sf21 cells
      Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
      Entrez Gene Number
      Entrez Gene SummaryThis gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.
      Gene Symbol
      • YES1
      • P61-YES
      • HsT441
      • Yes
      • c-yes
      • YES
      • p61-Yes
      Protein TargetYes
      Purification MethodNi2+/NTA-agarose
      Target Sub-FamilyTK
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P07947 # Promotes infectivity of Neisseria gonorrhoeae in epithelial cells by phosphorylating MCP/CD46.
      SIZE: 543 amino acids; 60801 Da
      SUBCELLULAR LOCATION: Cytoplasm, cytosol. Note=In epithelial cells infected with Neisseria gonorrhoeae, forms aggregates beneath bacterial microcolonies.
      PTM: Autophosphorylated.
      SIMILARITY: SwissProt: P07947 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
      Molecular Weight63kDa
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assuranceroutinely evaluated by phosphorylation of Poly (Glu4-Tyr) substrate
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage Conditions1 year at -70°C
      Packaging Information
      Material Size250 µg
      Material PackageAlso available in 10 μg size (cat#14-478) and in bulk (cat# 14-478-K).
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      14-478M 04053252740268

      Related Products & Applications

      Alternative Packsize

      Catalogue Number Description  
      14-478 Yes Protein, active, 10 µg Show Pricing & Availability

      Product Families

      Kinase & Phosphatase Products

      Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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      Categories

      Life Science Research > Proteins and Enzymes > Purified Kinases
      Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases