Millipore Sigma Vibrant Logo

672999 V-ATPase Inhibitor, KM91104 - Calbiochem

Overview

Key Spec Table

Empirical Formula
C₁₄H₁₂N₂O₄

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
672999-10MG
Limited Availability
Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Botol kaca 10 mg
      Price could not be retrieved
      Minimum Quantity is a multiple of
      Maximum Quantity is
      Upon Order Completion More Information
      You Saved ()
       
      Request Pricing
      Description
      OverviewA cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC50 of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC50 of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.
      Catalogue Number672999
      Brand Family Calbiochem®
      SynonymsH+-ATPase Inhibitor
      References
      ReferencesKartner, N., et al. 2010. J. Biol. Chem. 285, 37476.
      Product Information
      FormOff-white solid
      Hill FormulaC₁₄H₁₂N₂O₄
      Chemical formulaC₁₄H₁₂N₂O₄
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Biological Information
      Purity>98% by HPLC
      Storage and Shipping Information
      Ship Code Shipped with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      672999-10MG 04055977184143