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574105 Sulindac Sulfone

Sulindac Sulfone MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (Z)-5-Fluoro-2-methyl-1[p-(methylsulfonyl)benzylidene]indene-3-acetic Acid, Exisulind, FGN-1

Primary Target: cell growth
574105
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      59864-04-9C₂₀H₁₇FO₄S
      Description
      Overview

      This product has been discontinued.





      A cell-permeable sulfone metabolite of Sulindac (Cat. No. 574100) that has anticancer properties but lacks cyclooxygenase (COX) inhibitory activity. Also inhibits cell growth and induces apoptosis.
      Catalogue Number574105
      Brand Family Calbiochem®
      Synonyms(Z)-5-Fluoro-2-methyl-1[p-(methylsulfonyl)benzylidene]indene-3-acetic Acid, Exisulind, FGN-1
      References
      ReferencesGoluboff, E.T., et al. 1999. Urology 63, 440.
      Lim, J.T., et al. 1999. Biochem. Pharmacol. 58, 1097.
      Piazza, G.A., et al. 1995. Cancer Res. 55, 3110.
      Product Information
      CAS number59864-04-9
      FormYellow solid
      Hill FormulaC₂₀H₁₇FO₄S
      Chemical formulaC₂₀H₁₇FO₄S
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary Targetcell growth
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      574105 0

      Documentation

      Sulindac Sulfone Certificates of Analysis

      TitleLot Number
      574105

      References

      Reference overview
      Goluboff, E.T., et al. 1999. Urology 63, 440.
      Lim, J.T., et al. 1999. Biochem. Pharmacol. 58, 1097.
      Piazza, G.A., et al. 1995. Cancer Res. 55, 3110.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-September-2007 JSW
      Synonyms(Z)-5-Fluoro-2-methyl-1[p-(methylsulfonyl)benzylidene]indene-3-acetic Acid, Exisulind, FGN-1
      DescriptionA cell-permeable sulfone metabolite of Sulindac (Cat. No. 574100) that has anticancer properties but lacks cyclooxygenase (COX) inhibitory activity. Also inhibits cell growth and induces apoptosis.
      FormYellow solid
      CAS number59864-04-9
      Chemical formulaC₂₀H₁₇FO₄S
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityDMSO (25 mg/ml) or Ethanol (3 mg/ml)
      Storage +15°C to +30°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesGoluboff, E.T., et al. 1999. Urology 63, 440.
      Lim, J.T., et al. 1999. Biochem. Pharmacol. 58, 1097.
      Piazza, G.A., et al. 1995. Cancer Res. 55, 3110.