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05-23-0657 [Sar⁹, Met(O₂)¹¹]-Substance P

05-23-0657
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      110880-55-2C₆₄H₁₀₀N₁₈O₁₅S
      Description
      OverviewSelective NK-1 receptor agonist. Stimulates the formation of inositol phosphate (EC50 = 3.8 nM) and enhances taurine release (EC50 = 7.4 nM) from human astrocytoma cell line.
      Catalogue Number05-23-0657
      Brand Family Calbiochem®
      SynonymsRPKPQQFFSarLM(O₂)
      References
      ReferencesOury-Donat, F., et al. 1994. J. Neurochem. 62, 1399. Rouissi, N., et al. 1993. Life Sci. 52, L103. Giuliani, S., et al. 1988. Eur. J. Pharmacol. 150, 377.
      Product Information
      CAS number110880-55-2
      FormLyophilized
      Hill FormulaC₆₄H₁₀₀N₁₈O₁₅S
      Chemical formulaC₆₄H₁₀₀N₁₈O₁₅S
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met(O₂)-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 to months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      05-23-0657 0

      Documentation

      [Sar⁹, Met(O₂)¹¹]-Substance P Certificates of Analysis

      TitleLot Number
      05-23-0657

      References

      Reference overview
      Oury-Donat, F., et al. 1994. J. Neurochem. 62, 1399. Rouissi, N., et al. 1993. Life Sci. 52, L103. Giuliani, S., et al. 1988. Eur. J. Pharmacol. 150, 377.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      SynonymsRPKPQQFFSarLM(O₂)
      DescriptionSelective NK-1 receptor agonist. Stimulates the formation of inositol phosphate (EC50 = 3.8 nM) and enhances taurine release (EC50 = 7.4 nM) from human astrocytoma cell line.
      FormLyophilized
      CAS number110880-55-2
      Chemical formulaC₆₄H₁₀₀N₁₈O₁₅S
      Peptide SequenceH-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met(O₂)-NH₂
      Purity≥98% by HPLC
      Solubility5% Acetic acid (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 to months at -20°C.
      Toxicity Standard Handling
      ReferencesOury-Donat, F., et al. 1994. J. Neurochem. 62, 1399. Rouissi, N., et al. 1993. Life Sci. 52, L103. Giuliani, S., et al. 1988. Eur. J. Pharmacol. 150, 377.