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Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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505986
Sigma-AldrichSR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem
SR95531 (Gabazine) - CAS 104104-50-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
A selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 µM). Also shown to block glycine receptors, but with low affinity (Kb = 190 µM).
Catalogue Number
505986
Brand Family
Calbiochem®
Synonyms
GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
References
References
Muroi, Y., et al. 2009. Biophys. J.96, 499. Beato, M., et al. 2007. J. Physiol.580, 171. Uchida, I., et al. 1996. Eur. J. Pharmacol.307, 89.
Muroi, Y., et al. 2009. Biophys. J.96, 499. Beato, M., et al. 2007. J. Physiol.580, 171. Uchida, I., et al. 1996. Eur. J. Pharmacol.307, 89.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
20-September-2013 JSW
Synonyms
GABAA Receptor Antagonist, SR-95531, Gabazine, SR95531, SR 95531
Description
A selective, competitive antagonist of GABAA receptor (IC50 = 440 nM) that does not affect pentobarbitone or etomidate- induced currents even at high concentrations (~100 mM). Also shown to block glycine receptors, but with low affinity (Kb = 190 mM).
Form
White solid
CAS number
104104-50-9
Chemical formula
C₁₅H₁₇N₃O₃•HBr
Structure formula
Purity
≥98% by HPLC
Solubility
H₂O (25 mM)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Muroi, Y., et al. 2009. Biophys. J.96, 499. Beato, M., et al. 2007. J. Physiol.580, 171. Uchida, I., et al. 1996. Eur. J. Pharmacol.307, 89.
