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573112 SPDP

573112
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Purity
      68181-17-9≥95% by HPLC
      Description
      Overview

      This product has been discontinued.



      A heterobifunctional cross-linker. Reagent similar to SATA, useful for introducing protected thiol groups into a variety of proteins. Treatment with DTT releases the chromophore 2-pyridylthione and a mercaptopropionyl-modified amine. This thiolated biomolecule can then be coupled to a second biomolecule through an iodoacetamide or maleimide group. In addition, the thiolated biomolecule can be reacted with a second pyridyldisulfide-containing biomolecule.

      Catalogue Number573112
      Brand Family Calbiochem®
      SynonymsSuccinimidyl 3-(2-pyridyldithio)propionate
      References
      ReferencesVallera, D.A., et al. 1997. J. Immunol. Methods 197, 69.
      Kincaid, R.L., et al. 1988. Methods Enzymol. 159, 605.
      Product Information
      CAS number68181-17-9
      FormOff-white solid
      Hill FormulaC₁₂H₁₂N₂O₄S₂
      Chemical formulaC₁₂H₁₂N₂O₄S₂
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      573112 0

      Documentation

      SPDP MSDS

      Title

      Safety Data Sheet (SDS) 

      SPDP Certificates of Analysis

      TitleLot Number
      573112

      References

      Reference overview
      Vallera, D.A., et al. 1997. J. Immunol. Methods 197, 69.
      Kincaid, R.L., et al. 1988. Methods Enzymol. 159, 605.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision08-June-2009 RFH
      SynonymsSuccinimidyl 3-(2-pyridyldithio)propionate
      DescriptionA heterobifuntional cross-linker. Reagent similar to SATA, used to introduce protected thiol groups into a variety of proteins. Treatment with DTT releases chromophore 2-pyridylthione and mercaptopropionyl-modified amine. This thiolated biomolecule can then be coupled to a second biomolecule through an iodoacetamide or maleimide group. In addition, the thiolated biomolecule can be reacted with a second pyridyldisulfide-containing biomolecule.
      FormOff-white solid
      CAS number68181-17-9
      Chemical formulaC₁₂H₁₂N₂O₄S₂
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMF (10 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Irritant
      ReferencesVallera, D.A., et al. 1997. J. Immunol. Methods 197, 69.
      Kincaid, R.L., et al. 1988. Methods Enzymol. 159, 605.