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530006 Prion Protein, His•Tag®, Human, Recombinant, E. coli

Prion Protein, His•Tag®, Human, Recombinant, E. coli MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhPrPc

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530006
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Overview

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530006-100UG
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      Description
      OverviewRecombinant, human prion protein (amino acids 23-231) fused to a His•Tag® sequence and expressed in E. coli. Useful as an antigen standard in immunochemical detection of Creutzfeldt-Jakob Disease (CJD).
      Catalogue Number530006
      Brand Family Calbiochem®
      SynonymsrhPrPc
      References
      ReferencesCalzolai, L., and Zahn, R. 2003. J. Biol. Chem. 278, 35592.
      Prusiner, S.B. 1998. Proc. Natl. Acad. Sci. USA 95, 13363.
      Swietnicki, W., et al. 1997. J. Biol. Chem. 272, 27517.
      Pan, K.M., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 10962.
      Basler, K., et al. 1986. Cell 46, 417.
      Product Information
      FormLiquid
      FormulationIn 10 mM sodium acetate, pH 4.0.
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by SDS-PAGE
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      530006-100UG 04055977269321

      Documentation

      Prion Protein, His•Tag®, Human, Recombinant, E. coli MSDS

      Title

      Safety Data Sheet (SDS) 

      Prion Protein, His•Tag®, Human, Recombinant, E. coli Certificates of Analysis

      TitleLot Number
      530006

      References

      Reference overview
      Calzolai, L., and Zahn, R. 2003. J. Biol. Chem. 278, 35592.
      Prusiner, S.B. 1998. Proc. Natl. Acad. Sci. USA 95, 13363.
      Swietnicki, W., et al. 1997. J. Biol. Chem. 272, 27517.
      Pan, K.M., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 10962.
      Basler, K., et al. 1986. Cell 46, 417.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision29-August-2008 RFH
      SynonymsrhPrPc
      DescriptionRecombinant, human prion protein (amino acids 23-231) fused to a His•Tag® sequence and expressed in E. coli. Prion diseases or transmissible spongiform encephalopathies are neurodegenerative diseases that affect both humans and animals. All prion diseases share the same molecular pathogenic mechanism that involves conversion of normal cellular prion protein (PrPc) into a form that is insoluble in non-ionic detergent and partially resistant to proteases (PrPsc). Useful as an antigen standard in immunochemical detection of Creutzfeldt-Jakob Disease (CJD).
      FormLiquid
      FormulationIn 10 mM sodium acetate, pH 4.0.
      Purity≥95% by SDS-PAGE
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesCalzolai, L., and Zahn, R. 2003. J. Biol. Chem. 278, 35592.
      Prusiner, S.B. 1998. Proc. Natl. Acad. Sci. USA 95, 13363.
      Swietnicki, W., et al. 1997. J. Biol. Chem. 272, 27517.
      Pan, K.M., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 10962.
      Basler, K., et al. 1986. Cell 46, 417.