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141350 Polivinil alkohol 4-88

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaGrade Value
9002-89-5(C₂H₄O)nPh Eur,ChP,USP,JPE

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1413501000
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      Botol plastik 1 kg
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      1413509029
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          Karung Polietilen ganda 25 kg
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          1413509525
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              Karung Polietilen ganda 21 x 25 kg
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              Description
              Catalogue Number141350
              SynonymsPVA, PVOH
              References
              Product Information
              CAS number9002-89-5
              GradePh Eur,ChP,USP,JPE
              Hill Formula(C₂H₄O)n
              HS Code3905 30 00
              Quality LevelMQ500
              Applications
              Biological Information
              Physicochemical Information
              Melting Point160 - 240 °C
              Bulk density400 - 670 kg/m3
              Dimensions
              Materials Information
              Toxicological Information
              LD 50 oralLD50 Tikus > 2000 mg/kg
              Safety Information according to GHS
              RTECSTR8100000
              Storage class10 - 13 Cairan dan padatan lain
              WGKWGK 1 agak berbahaya untuk air
              Disposal3
              Reagen organik yang relatif tidak aktif harus dikumpulkan dalam kategori A. Jika terhalogenasi, harus ditempatkan dalam Kategori B. Untuk residu padat gunakan Kategori C.
              Safety Information
              Product Usage Statements
              Storage and Shipping Information
              StorageSimpan pada +15°C hingga +25°C.
              Packaging Information
              Transport Information
              Supplemental Information
              Specifications
              Identity (IR spectrum)passes test
              Identity (Viscosity)passes test
              Identity (Reaction with iodine)passes test
              Identity (Reaction with iodine and boric acid)passes test
              Identity (Reaction with ethanol)passes test
              Appearance of solution (40 g/l, water)passes test
              Appearance of solution (50 g/l, water)passes test
              Water-insoluble matter (40 g/l, water)≤ 0.1 %
              pH-Value (40 g/l; water)5.0 - 6.5
              Viscosity (40 g/l; water)3.4 - 4.6 mPa∙s
              As (Arsenic)≤ 2 ppm
              As (Arsenic) (ChP)≤ 2 ppm
              Heavy metals (as Pb)≤ 10 ppm
              Heavy metals (as Pb) (ChP)≤ 10 ppm
              Crotonaldehyde (GC)≤ 10 ppm
              Acetic acid (alkalimetric)≤ 0.5 %
              Methanol (GC)≤ 1.0 %
              Methanol (GC) (JPE)¹≤ 1.0 %
              Methyl acetate (GC)≤ 1.0 %
              Other residual solvents (ICH Q3C)excluded by production process
              Ester value130 - 150
              Degree of hydrolysis (USP, ChP)85 - 89 %
              Degree of hydrolysis (JPE)78 - 96 %
              Acid value≤ 3.0
              Saponification value132 - 152
              Residue on ignition≤ 1.0 %
              Sulfated ash≤ 1.0 %
              Loss on Drying (105 °C)≤ 5.0 %
              Microbiological purity (Total aerobic microbial count (TAMC))≤ 100 CFU/g
              Microbiological purity (Total yeast and mould count (TYMC))≤ 100 CFU/g
              Bile-tolerant gram-negative bacteria (absent in 1 g)conforms
              Escherichia coli (absent in 1 g)conforms
              Pseudomonas aeruginosa (absent in 1 g)conforms
              Staphylococcus aureus (absent in 1 g)conforms
              Candida albicans (absent in 1 g)conforms
              Salmonella (absent in 10 g)conforms
              Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
              ¹ Value measured in qualified external laboratory
              Corresponds to Ph Eur,ChP,USP,JPE
              Global Trade Item Number
              Catalogue Number GTIN
              1413501000 04027269063689
              1413509029 04027269074876
              1413509525 04027269142940

              Documentation

              Material Qualification Dossier

              TitleVersion
              10.0

              Quality Management Dossier (Open Access)

              Title

              Operational Excellence Dossier

              Title

              Polivinil alkohol 4-88 MSDS

              Title

              Safety Data Sheet (SDS) 

              Polivinil alkohol 4-88 Certificates of Analysis

              Product Number PackagingSpecificationLot Number
              1413501000 Botol plastikPDF Specification Document
              1413509029 Karung Polietilen gandaPDF Specification Document
              1413509525 Karung Polietilen gandaPDF Specification Document

              Certificates

              Title

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              Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > Surfactants and Stabilizers
              Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Thickeners
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              Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > Binders and Fillers
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              Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > Surfactants and Stabilizers