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Buffer Detection Kit for Magnetic Beads
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506125
Sigma-AldrichParoxetine Hydrochloride - CAS 110429-35-1 - Calbiochem
Paroxetine Hydrochloride is a very potent uptake inhibitor highly selective for 5-HT transporter.
More>>Paroxetine Hydrochloride is a very potent uptake inhibitor highly selective for 5-HT transporter. Less<<
Paroxetine Hydrochloride - CAS 110429-35-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
A very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
Catalogue Number
506125
Brand Family
Calbiochem®
Synonyms
5-HT transporter, Paroxetine, Paxil
References
References
Brittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology.38, 407. Bourin, M., et al. 2001. CNS Drug Rev.7, 25. Thomas, R., et al. 1997. Psychopharmacology (Berl).93, 193.
Brittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology.38, 407. Bourin, M., et al. 2001. CNS Drug Rev.7, 25. Thomas, R., et al. 1997. Psychopharmacology (Berl).93, 193.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
17-December-2018 JSW
Synonyms
5-HT transporter, Paroxetine, Paxil
Description
A very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
Form
White solid
CAS number
110429-35-1
Chemical formula
C₁₉H₂₀FNO₃·HCl
Structure formula
Purity
≥99% by HPLC
Solubility
DMSO
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Brittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology.38, 407. Bourin, M., et al. 2001. CNS Drug Rev.7, 25. Thomas, R., et al. 1997. Psychopharmacology (Berl).93, 193.
