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512731 Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity.

Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Neomycin E

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      Overview

      Key Spec Table

      CAS #Empirical Formula
      1263-89-4C₂₃H₄₅N₅O₁₄ · H₂SO₄
      Description
      OverviewAn aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates that paromomycin binding to the A-site of 16S rRNA induces a local conformational change, suggesting a mechanism for aminoglycoside action on protein translation. Also exhibits anti-protozoal properties.
      Potency: ≥675 µg/mg.
      Catalogue Number512731
      Brand Family Calbiochem®
      SynonymsNeomycin E
      References
      ReferencesVanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.
      Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.
      Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333.
      Product Information
      CAS number1263-89-4
      FormOff-white solid
      Hill FormulaC₂₃H₄₅N₅O₁₄ · H₂SO₄
      Chemical formulaC₂₃H₄₅N₅O₁₄ · H₂SO₄
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Safety Information according to GHS
      RTECSWK2320000
      Safety Information
      R PhraseR: 20/21/22

      Harmful by inhalation, in contact with skin and if swallowed.
      S PhraseS: 22-24/25-36/37/39-45

      Do not breathe dust.
      Avoid contact with skin and eyes.
      Wear suitable protective clothing, gloves and eye/face protection.
      In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Harmful
      Storage +15°C to +30°C
      Do not freeze Ok to freeze
      Global Trade Item Number
      Catalogue Number GTIN
      512731 0