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475914 Nystatin, Streptomyces noursei - CAS 1400-61-9 - Calbiochem

Nystatin, Streptomyces noursei, CAS 1400-61-9, is an antifungal antibiotic effective against yeast and mycoplasma. Acts as a cation-selective ionophore that exhibits selectivity for Na+.

Nystatin, Streptomyces noursei - CAS 1400-61-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Mycostatin

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475914
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1400-61-9C₄₇H₇₅NO₁₇

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          Description
          OverviewA polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation-selective ionophore that exhibits selectivity for Na+. Increases the activity of Na+ - K+ pump.
          Catalogue Number475914
          Brand Family Calbiochem®
          SynonymsMycostatin
          References
          ReferencesGruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
          Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
          Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
          Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.
          Product Information
          CAS number1400-61-9
          FormOff-white to yellow solid
          Hill FormulaC₄₇H₇₅NO₁₇
          Chemical formulaC₄₇H₇₅NO₁₇
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          ApplicationNystatin, Streptomyces noursei, CAS 1400-61-9, is an antifungal antibiotic effective against yeast and mycoplasma. Acts as a cation-selective ionophore that exhibits selectivity for Na+.
          Biological Information
          Biological activityPotency: ≥3000 units/mg (anhydrous).
          Purity≥95% by HPLC (sum of two peaks)
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          RTECSRF5950000
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          475914-1GM 04055977184167
          475914-5GM 07790788050542

          Documentation

          Nystatin, Streptomyces noursei - CAS 1400-61-9 - Calbiochem MSDS

          Title

          Safety Data Sheet (SDS) 

          Nystatin, Streptomyces noursei - CAS 1400-61-9 - Calbiochem Certificates of Analysis

          TitleLot Number
          475914

          References

          Reference overview
          Gruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
          Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
          Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
          Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision10-December-2016 JSW
          SynonymsMycostatin
          DescriptionA polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation selective ionophore that exhibits selectivity for Na+. Increases the activity of the Na+-K+ pump. Suggested concentration is 50 µg/ml.
          FormOff-white to yellow solid
          CAS number1400-61-9
          RTECSRF5950000
          Chemical formulaC₄₇H₇₅NO₁₇
          Structure formulaStructure formula
          Purity≥95% by HPLC (sum of two peaks)
          Biological activityPotency: ≥3000 units/mg (anhydrous).
          SolubilityDMSO (50 mg/ml)
          Storage Protect from light
          +2°C to +8°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          Merck USA index14, 6736
          ReferencesGruwel, M.L., et al. 1995. Am J. Physiol. 268, H351.
          Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
          Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol. 4, 1855.
          Skolink, P.R., et al. 1989. J. Infect. Dis. 160, 1056.

          Related Products & Applications

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          Catalogue Number Description  
          475921 Nystatin, Streptomyces noursei, Sterile, Tissue Culture Grade - CAS 1400-61-9 - Calbiochem Show Pricing & Availability

          Categories

          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Antibiotics > Antifungal Agents
          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Ionophores