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500299 Nikotinamida

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
98-92-0202-713-4C₆H₆N₂O122.13 g/molPh Eur,BP,USP,JP,FCC

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      Karton fiber 20 kg
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      Description
      Catalogue Number500299
      SynonymsNicotinamide, Niacinamide, 3-Pyridinecarboxamide
      References
      Product Information
      CAS number98-92-0
      EC number202-713-4
      GradePh Eur,BP,USP,JP,FCC
      Hill FormulaC₆H₆N₂O
      Molar Mass122.13 g/mol
      HS Code2936 29 00
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Boiling point150 - 160 °C (0.0007 hPa)
      Density1.40 g/cm3 (25 °C)
      Flash point150 °C
      Ignition temperature480 °C
      Melting Point130 °C (menyublim)
      pH value6.0 - 7.5 (50 g/l, H₂O, 20 °C)
      Bulk density360 kg/m3
      Solubility691 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Tikus 3530 - 3540 mg/kg
      LD 50 dermalLD50 Kelinci > 2000 mg/kg
      Safety Information according to GHS
      Hazard Pictogram(s) Hazard Pictogram(s)
      Hazard Statement(s)H319: Menyebabkan iritasi mata yang serius.
      Precautionary Statement(s)P264: Cuci kulit dengan seksama setelah menangani.
      P280: Pakai perlindungan mata/ perlindungan muka.
      P305 + P351 + P338: JIKA TERKENA MATA : Bilas dengan seksama dengan air untuk beberapa menit. Lepaskan lensa kontak jika memakainya dan mudah melakukannya.Lanjutkan membilas.
      P337 + P313: Jika iritasi mata tidak segera sembuh: Cari pertolongan medis.
      Signal WordAwas
      RTECSQS3675000
      Storage class10 - 13 Cairan dan padatan lain
      WGKWGK 1 agak berbahaya untuk air
      Disposal3
      Reagen organik yang relatif tidak aktif harus dikumpulkan dalam kategori A. Jika terhalogenasi, harus ditempatkan dalam Kategori B. Untuk residu padat gunakan Kategori C.
      Safety Information
      Categories of dangermengiritasi
      Product Usage Statements
      Storage and Shipping Information
      StorageSimpan pada +15°C hingga +25°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
      Assay (HPLC, calc. on dried substance)98.5 - 101.0 %
      Identity (IR-spectrum) (Ph Eur)passes test
      Identity (IR-spectrum) (USP)passes test
      Identity (coloring 1)passes test
      Identity (coloring 2)passes test
      Identity (UV/VIS-Spectrum)passes test
      AppearanceWhite to almost white, crystalline powder
      Appearance of solution (50 g/l; water)Clear, colourless, not more intense in color than reference solution BY₇
      pH (50 g/l; water)6.0 - 7.5
      Melting range (lower value)≥ 128 °C
      Melting range (upper value)≤ 131 °C
      Absorption ratio (A 245 nm/A 262 nm)0.63 - 0.67
      Chloride (Cl)≤ 210 ppm
      Sulfate (SO₄)≤ 190 ppm
      Pb (Lead)≤ 2 ppm
      Residual solvents (ICH Q3C)excluded by production process
      Readily carbonisable substancepasses test
      Related substances (HPLC) (Major unspecified impurity)≤ 0.10 %
      Related substances (HPLC) (Sum of all impurities)≤ 0.2 %
      Sulfated ash (600 °C)
      ≤ 0.1 %
      Loss on drying (Vacuum; 18 h)
      ≤ 0.5 %
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph Eur, BP, USP, FCC, JP.
      Sulfated ash (600 °C)
      ≤ 0.1 %
      Loss on drying (Vacuum; 18 h)
      ≤ 0.5 %
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph Eur, BP, USP, FCC, JP.
      Global Trade Item Number
      Catalogue Number GTIN
      5002999020 04022536722382

      Documentation

      Material Qualification Dossier

      TitleVersion
      5.0

      Quality Management Dossier (Open Access)

      Title

      Operational Excellence Dossier

      Title

      Nikotinamida MSDS

      Title

      Safety Data Sheet (SDS) 

      Nikotinamida Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      5002999020 Karton fiberPDF Specification Document

      Certificates

      Title