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480001 NDSB-195 - CAS 160255-06-1 - Calbiochem

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins.

NDSB-195 - CAS 160255-06-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Dimethylethylammonium Propane Sulfonate

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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
160255-06-1C₇H₁₇NO₃S

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          Description
          OverviewA non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Does not absorb significantly in the near-UV range. Easily removed by dialysis.
          Catalogue Number480001
          Brand Family Calbiochem®
          SynonymsDimethylethylammonium Propane Sulfonate
          References
          ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
          Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
          Vuillard, L., et al. 1995. Biochem. J. 305, 337.
          Vuillard, L., et al. 1994. FEBS Lett. 353, 294.
          Product Information
          CAS number160255-06-1
          FormWhite solid
          Hill FormulaC₇H₁₇NO₃S
          Chemical formulaC₇H₁₇NO₃S
          Hygroscopic Hygroscopic
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥95% by TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 36/37/38

          Irritating to eyes, respiratory system and skin.
          S PhraseS: 26-36

          In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
          Wear suitable protective clothing.
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Irritant
          Storage +15°C to +30°C
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          480001-25GM 04055977201758
          480001-5GM 04055977201765

          Documentation

          NDSB-195 - CAS 160255-06-1 - Calbiochem MSDS

          Title

          Safety Data Sheet (SDS) 

          NDSB-195 - CAS 160255-06-1 - Calbiochem Certificates of Analysis

          TitleLot Number
          480001

          References

          Reference overview
          Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
          Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
          Vuillard, L., et al. 1995. Biochem. J. 305, 337.
          Vuillard, L., et al. 1994. FEBS Lett. 353, 294.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision13-April-2011 RFH
          SynonymsDimethylethylammonium Propane Sulfonate
          DescriptionA member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb significantly in the near UV range. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis.
          FormWhite solid
          CAS number160255-06-1
          Chemical formulaC₇H₁₇NO₃S
          Structure formulaStructure formula
          Purity≥95% by TLC
          SolubilityH₂O
          Storage +15°C to +30°C
          Hygroscopic
          Do Not Freeze Ok to freeze
          Toxicity Irritant
          ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
          Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
          Vuillard, L., et al. 1995. Biochem. J. 305, 337.
          Vuillard, L., et al. 1994. FEBS Lett. 353, 294.

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          Categories

          Life Science Research > Inhibitors and Biochemicals > Biochemicals > Detergents > Non-Detergent Sulfobetaines