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FCMAB208P Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57

Milli-Mark Anti-CD79αcy-PE Antibody, clone HM57 is an antibody against CD79αcy for use in FC.

Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P11912
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FCMAB208P
100 tests  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HFCMPhycoerythrinMonoclonal Antibody
      Description
      Catalogue NumberFCMAB208P
      Trade Name
      • Milli-Mark
      DescriptionMilli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57
      Alternate Names
      • B-cell antigen receptor complex-associated protein alpha chain
      • Ig-alpha
      • MB-1 membrane glycoprotein
      • Surface IgM-associated protein
      • Membrane-bound immunoglobulin-associated protein
      Background InformationCD79 is a disulphide-linked transmembrane heterodimer with a molecular mass of 82-95 kDa belonging to the immunoglobulin superfamily. It comprises the two glycoproteins, CD79α, with a molecular mass of 40-45 kDa, and CD79β, with a molecular mass of 37 kDa. CD79 is non-covalently associated with surface Ig, forming the B-cell receptor complex, which is required for antigen recognition. The expression of CD79 is largely restricted to B-lineage cells (Pilozzi,1998). In precursor B cells, the CD79 protein chains are already expressed in the cytoplasm (CyCD79). Surface expression of CD79 begins at the pro-B cell stage and persists throughout the B-cell differentiation. CD79α is more strongly expressed by B cells in the follicular mantle zone than by germinal centre B cells, suggesting that activation of mature B cells downregulates CD79 expression. CD79 expression ceases around the onset of plasma cell differentiation, with only a proportion of plasma cells containing CD79 (Comans-Bitter, 1997)(Nakamura, 1997). The HM57 antibody was clustered as Anti-CD79αcy at the Fifth International Workship on Human Leucocyte Differentiation Antigens (Engel, 1995).
      References
      Product Information
      FormatPhycoerythrin
      Control
      • Human Lymphocytes
      PresentationPurified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
      Quality LevelMQ100
      Applications
      ApplicationMilli-Mark Anti-CD79αcy-PE Antibody, clone HM57 is an antibody against CD79αcy for use in FC.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenSynthetic peptide sequence comprising amino acids 202-216 of the CD79α protein. This oligopeptide represents an intra-cytoplasmic C-terminal part of the protein.
      CloneHM57
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityAntibody recognizes Human CD79αcy antigen.
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Purification MethodProtein A Purfied
      UniProt Number
      Molecular Weight 82-95 kDa (Pilozzi,1998)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by flow cytometry using human lymphocytes
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
      Packaging Information
      Material Size100 tests
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      FCMAB208P 04053252412059

      Documentation

      Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57 MSDS

      Title

      Safety Data Sheet (SDS) 

      Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57 Certificates of Analysis

      TitleLot Number
      Milli-Mark Anti-CD79cy-PE, clone HM57 - 2028591 2028591
      Milli-Mark Anti-CD79cy-PE, clone HM57 - 2036114 2036114
      Milli-Mark Anti-CD79cy-PE, clone HM57 - 2188555 2188555
      Milli-Mark Anti-CD79cy-PE, clone HM57 - 2246797 2246797
      Milli-Mark Anti-CD79cy-PE, clone HM57 - NG1947166 NG1947166
      Milli-Mark Anti-CD79cy-PE, clone HM57 - NRG1781534 NRG1781534
      Milli-Mark™ Anti-CD79αcy-PE, -2645972 2645972
      Milli-Mark™ Anti-CD79αcy-PE, -2790086 2790086
      Milli-Mark™ Anti-CD79cy-PE, clone HM57 - 2291723 2291723
      Milli-Mark™ Anti-CD79cy-PE, clone HM57 - 2377618 2377618