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48-602MAG
Buffer Detection Kit for Magnetic Beads
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474780
Sigma-AldrichMG-115 - CAS 133407-86-0 - Calbiochem
Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively).
More>>Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively). Less<<
MG-115 - CAS 133407-86-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively). Specifically inhibits the chymotrypsin-like activity of the proteasome and induces apoptosis in Rat-1 and PC12 cells.
Catalogue Number
474780
Brand Family
Calbiochem®
Synonyms
Carbobenzoxy-L-leucyl-L-leucyl-L-norvalinal, Z-LL-Nva-CHO, Proteasome Inhibitor XII
References
References
Lopes, U.G., et al. 1997. J. Biol. Chem. 272, 12893. Lee, D.H., and Goldberg, A.L. 1996. J. Biol. Chem.271, 27280. Palombella, V.J., et al. 1994. Cell 78, 773. Rock, K.L., et al. 1994. Cell 78, 761. Vinitsky, A., et al. 1992. Biochemistry 31, 9421.
MG-115 - CAS 133407-86-0 - Calbiochem Certificates of Analysis
Title
Lot Number
474780
References
Reference overview
Lopes, U.G., et al. 1997. J. Biol. Chem. 272, 12893. Lee, D.H., and Goldberg, A.L. 1996. J. Biol. Chem.271, 27280. Palombella, V.J., et al. 1994. Cell 78, 773. Rock, K.L., et al. 1994. Cell 78, 761. Vinitsky, A., et al. 1992. Biochemistry 31, 9421.
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
01-April-2011 RFH
Synonyms
Carbobenzoxy-L-leucyl-L-leucyl-L-norvalinal, Z-LL-Nva-CHO, Proteasome Inhibitor XII
Description
Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively).
Form
White solid
CAS number
133407-86-0
Chemical formula
C₂₅H₃₉N₃O₅
Peptide Sequence
Z-Leu-Leu-Nva-CHO
Structure formula
Purity
≥90% by HPLC
Solubility
DMSO (50 mg/ml)
Storage
Protect from light
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Lopes, U.G., et al. 1997. J. Biol. Chem. 272, 12893. Lee, D.H., and Goldberg, A.L. 1996. J. Biol. Chem.271, 27280. Palombella, V.J., et al. 1994. Cell 78, 773. Rock, K.L., et al. 1994. Cell 78, 761. Vinitsky, A., et al. 1992. Biochemistry 31, 9421.
