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368068 Granzyme B Substrate IX, Fluorogenic

368068
  
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      Overview

      Description
      Overview

      This product has been discontinued.





      A fluorogenic substrate for granzyme B (kcat/Km = 3,330 M-1s-1) that also recognizes granzyme B variants (kcat/Km = 55 M-1s-1 for R192A and kcat/Km = 8.8 M-1s-1 for R192E).
      Catalogue Number368068
      Brand Family Calbiochem®
      SynonymsAc-IEPD-AMC
      References
      ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
      Product Information
      FormLyophilized
      Hill FormulaC₃₂H₄₁N₅O₁₁
      Chemical formulaC₃₂H₄₁N₅O₁₁
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Emission max.
      Excitation max.
      Peptide SequenceAc-Ile-Glu-Pro-Asp-AMC
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      368068 0