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345736 Ganglioside GD1a, Disialo, Diammonium Salt, Bovine Brain - Calbiochem

Useful as a differentiation marker of tumor cell growth.

Ganglioside GD1a, Disialo, Diammonium Salt, Bovine Brain - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Cer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄

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345736
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₈₄H₁₄₆N₄O₃₉ · 2NH₄

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      Description
      OverviewUseful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM1 by bacterial and mammalian neuraminidases without detergent or bile salts. Note: the moleculare weight is based on on stearoyl-18:0.
      Catalogue Number345736
      Brand Family Calbiochem®
      SynonymsCer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
      References
      ReferencesLongee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
      Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
      Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
      Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.
      Product Information
      ATP CompetitiveN
      FormLyophilized
      Hill FormulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
      Chemical formulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetProtein kinase C
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableN
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      R PhraseR: 36/37/38

      Irritating to eyes, respiratory system and skin.
      S PhraseS: 26-36

      In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
      Wear suitable protective clothing.
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      345736-1MG 04055977193831

      Documentation

      Ganglioside GD1a, Disialo, Diammonium Salt, Bovine Brain - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      Ganglioside GD1a, Disialo, Diammonium Salt, Bovine Brain - Calbiochem Certificates of Analysis

      TitleLot Number
      345736

      References

      Reference overview
      Longee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
      Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
      Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
      Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.

      Brochure

      Title
      Gangliosides Technical Bulletin
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-September-2007 JSW
      SynonymsCer-Glc-Gal(NeuAc)-GalNAc-Gal-NeuAc ·2NH₄
      DescriptionDisialoganglioside prepared from bovine gray matter. Useful as a differentiation marker of tumor cell growth. Protein kinase C inhibitor. Readily converted to GM1 by bacterial and mammalian sialidases without detergent or bile salts. One mole yields 2 moles of sialic acid by thiobarbituric acid assay. The molecular weight is based on stearoyl-18:0.

      Note: This product is not to be used for animal treatment, in vivo research, or in any other contact procedure with livestock.
      FormLyophilized
      Chemical formulaC₈₄H₁₄₆N₄O₃₉ · 2NH₄
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityChloroform:Methanol (2:1) or DMSO. For use in aqueous systems, dissolve in a small amount of DMSO and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions may be filter sterilized.
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.
      Toxicity Irritant
      ReferencesLongee, D.C., et al. 1991. Acta Neuropathologica 82, 45.
      Livingston, P.O., et al. 1987. Proc Natl. Acad. Sci. USA 84, 2911.
      Kundu, S.K., and Scott, D.D. 1982. J. Chromato. 232, 19.
      Wakomari, S. 1981. Annu. Rev. Biochem. 50, 733.