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341283 Factor P, Human

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341283
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341283-250UG
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      Ampul plastik 250 μg
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      Description
      OverviewNative factor P from human serum. Glycoprotein found in blood plasma in dimeric, trimeric, and tetrameric forms with M.W. of 92 kDa, 138 kDa, and 184 kDa, respectively. Present in normal human serum at about 20 µg/ml. Regulatory protein of the alternative pathway of complement activation. Accelerates complement activation by binding to and stabilizing the alternative pathway C3 and C5 convertase enzymes.
      Catalogue Number341283
      Brand Family Calbiochem®
      SynonymsProperdin
      References
      ReferencesPangburn, M.K., et al. 1988. Methods Enzymol. 162, 639.
      Smith, C.A., et al. 1984. J. Biol. Chem. 259, 4582.
      Product Information
      FormLiquid
      FormulationIn PBS, pH 7.2.
      Quality LevelMQ100
      Biological Information
      Purity≥90% by SDS-PAGE
      SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Physicochemical Information
      ContaminantsIgG, IgA, IgM, Factor I, Factor B, Factor H, C3, C4, or albumin (by Ouchterlony): ≤trace amounts
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Global Trade Item Number
      Catalogue Number GTIN
      341283-250UG 04055977215595