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324788 DAPK Inhibitor - CAS 315694-89-4 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
315694-89-4C₁₇H₁₂N₂O₂

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324788-10MG
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      Description
      OverviewAn oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 µM ATP), while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 µM.
      Catalogue Number324788
      Brand Family Calbiochem®
      Synonyms(4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor
      References
      ReferencesOkamoto, M., et al. 2009. J. Med. Chem. 52, 7323.
      Product Information
      CAS number315694-89-4
      FormYellow solid
      Hill FormulaC₁₇H₁₂N₂O₂
      Chemical formulaC₁₇H₁₂N₂O₂
      Quality LevelMQ100
      Biological Information
      Purity≥95% by HPLC
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Global Trade Item Number
      Catalogue Number GTIN
      324788-10MG 04055977216127