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324788 DAPK Inhibitor - CAS 315694-89-4 - Calbiochem

The DAPK Inhibitor, also referenced under CAS 315694-89-4, controls the biological activity of DAPK.

DAPK Inhibitor - CAS 315694-89-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor

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324788
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
315694-89-4C₁₇H₁₂N₂O₂

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324788-10MG
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      Description
      OverviewAn oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 µM ATP), while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 µM.
      Catalogue Number324788
      Brand Family Calbiochem®
      Synonyms(4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor
      References
      ReferencesOkamoto, M., et al. 2009. J. Med. Chem. 52, 7323.
      Product Information
      CAS number315694-89-4
      FormYellow solid
      Hill FormulaC₁₇H₁₂N₂O₂
      Chemical formulaC₁₇H₁₂N₂O₂
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      324788-10MG 04055977216127

      Documentation

      DAPK Inhibitor - CAS 315694-89-4 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      DAPK Inhibitor - CAS 315694-89-4 - Calbiochem Certificates of Analysis

      TitleLot Number
      324788

      References

      Reference overview
      Okamoto, M., et al. 2009. J. Med. Chem. 52, 7323.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-April-2011 RFH
      Synonyms(4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor
      DescriptionAn oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 µM ATP), while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 µM.
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number315694-89-4
      Chemical formulaC₁₇H₁₂N₂O₂
      Purity≥95% by HPLC
      SolubilityDMSO (25 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesOkamoto, M., et al. 2009. J. Med. Chem. 52, 7323.